ALZHEIMER'S DISEASE (AD)

This study is testing whether a blood test can help screen for Alzheimer's disease in older adults living in the community. Researchers will enroll 3,000 people aged 60-80 and measure specific blood markers. Those with abnormal results will receive further cognitive testing to se…

This study aims to improve how doctors detect early signs of Alzheimer's disease in people aged 60 and older. Researchers will use digital cognitive tests and blood-based biomarkers to help general practitioners and specialists identify those at risk. The goal is to make early di…

This study tests a medical device called Neuclare that is placed on the head to see if it can temporarily improve thinking and planning skills in people with mild cognitive impairment or very early Alzheimer's disease. About 138 adults aged 55 to 90 who are already on memory medi…

This observational study will follow 50,000 people with Alzheimer's or related dementias for many years, collecting medical information from routine doctor visits. Researchers hope to better understand how the disease progresses and how well treatments work in everyday practice. …

This study tests new methods to improve how dementia clinical trials are run. Researchers want to see if a combined score of thinking and daily function can better measure treatment effects. They will also check if blood proteins can predict who responds to the Alzheimer's drug d…

This study is testing whether a remote exercise and dementia care program works well for older adults with Down syndrome (over 35) and their caregivers. The program is delivered from home and aims to see if it's practical and helpful. About 40 participants will take part to check…

This study is testing a new 10-minute tool called CHRONOS to see how Alzheimer's disease affects a person's sense of time. Researchers will ask 40 people with Alzheimer's to complete tasks about timing, order, and memory. The goal is to find early signs of the disease and help do…

This study is creating a large collection of data and biological samples from people with and without neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's. Researchers will use this information to better understand how these diseases progress and to develop new treat…

This study tests a new PET scan tracer to measure a protein called Hsp90 in the brain. Hsp90 helps proteins fold correctly, and problems with this process are linked to Alzheimer's, Parkinson's, and ALS. Researchers will scan 48 people—healthy volunteers and patients—to see if th…

This study aims to validate a new serious game test called REALSoCog that helps detect social behavior problems in people with Alzheimer's disease, Lewy body dementia, or frontotemporal degeneration. Researchers will test 120 patients and their caregivers to see if the game can i…