Alport syndrome
Clinical trials for Alport syndrome explained in plain language.
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New drug aims to slow kidney failure in rare genetic disease
Disease control OngoingThis study tests an experimental drug called BAY 3401016 in 60 adults aged 18 to 45 with Alport syndrome, a rare genetic condition that damages kidneys, hearing, and eyes. The drug works by blocking a protein thought to cause kidney injury, with the goal of slowing the loss of ki…
Matched conditions: ALPORT SYNDROME
Phase 2 • Sponsor: Bayer • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New drug aims to plug kidney leaks in multiple diseases
Disease control OngoingThis phase 2 study tests the drug atrasentan in 103 adults with various kidney diseases that cause protein leakage, including IgA nephropathy and FSGS. Participants take a daily tablet to see if it reduces protein in urine, a sign of kidney damage. The goal is to find a new way t…
Matched conditions: ALPORT SYNDROME
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC