ADVANCED SOLID MALIGNANCIES
Clinical trials for ADVANCED SOLID MALIGNANCIES explained in plain language.
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New hope for advanced cancer? first human trial of BR115 begins
Disease control TerminatedThis early-stage study tests a new drug called BR115 in 120 adults with advanced solid tumors that have not responded to other treatments. The main goals are to check the drug's safety and find the right dose. Participants receive the drug weekly after an initial two doses in the…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: BioRay Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 10:27 UTC
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New shot form of cancer drug tested in advanced tumors
Disease control OngoingThis study tests a new way to give the cancer drug amivantamab as a shot under the skin instead of through an IV. It includes 158 adults with advanced solid tumors that may respond to this type of treatment. The main goals are to check safety and find the best dose for the shot f…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 26, 2026 08:20 UTC
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New hope for Hard-to-Treat cancers: first human trial launches
Disease control OngoingThis early-stage study tests a new drug called PRJ1-3024 in about 39 people with advanced solid tumors that have stopped responding to standard treatments. The main goal is to check the drug's safety and find the right dose. Researchers will also look for signs that the drug migh…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: Zhuhai Yufan Biotechnologies Co., Ltd • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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New triple therapy aims to shrink hard-to-treat cancers
Disease control OngoingThis early-phase study tests whether combining two immunotherapy drugs (tiragolumab and atezolizumab) with a special type of radiation (RadScopal) is safe and can help shrink advanced solid tumors. The trial includes 7 adults with metastatic or unresectable cancers who have run o…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New cancer drug interaction study: no cure, but key safety data
Knowledge-focused OngoingThis early-stage study looks at how the experimental drug saruparib affects other medications in people with advanced solid tumors that have not responded to standard treatments. About 41 participants will take saruparib along with common drugs to measure changes in drug levels i…
Matched conditions: ADVANCED SOLID MALIGNANCIES
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC