ADVANCED SOLID MALIGNANCIES

This early-stage study is testing a new way to give the cancer drug amivantamab—as an injection under the skin instead of through an IV. It aims to find a safe and effective dose for this injection method in people with advanced solid tumors that have not responded to other treat…

This is the first study in people to test a new drug called BR115 for advanced solid cancers. The main goal is to check the drug's safety, side effects, and how the body processes it, while also looking for early signs that it might help shrink tumors. It will involve about 120 a…

This is the first-ever study in humans of a new oral medication called PRJ1-3024 for people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how the body handles the drug. Researchers will also look for…

This early-stage study is testing the safety of a new combination treatment for people with advanced solid tumors that have spread. The treatment combines two immunotherapy drugs with a special type of targeted radiation. It is for patients who have very limited life expectancy a…

This early-stage study aims to understand how a new oral drug called saruparib interacts with other common medications in patients with advanced solid tumors. It will also test if different ways of making the pill affect how the body absorbs it. The main goal is to gather safety …