ADVANCED RENAL CELL CARCINOMA
Clinical trials for ADVANCED RENAL CELL CARCINOMA explained in plain language.
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New combo therapy for advanced kidney cancer under Real-World watch
Disease control OngoingThis study follows 311 adults with advanced kidney cancer who are receiving a combination of two drugs, cabozantinib and nivolumab, as their first treatment. Researchers are tracking how long patients live and how long the cancer stays under control in everyday medical practice. …
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Sponsor: Ipsen • Aim: Disease control
Last updated May 26, 2026 11:34 UTC
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New drug combo shows promise for tough kidney cancer
Disease control OngoingThis study tests a combination of two drugs—nivolumab and a radioactive antibody called 177Lu-girentuximab—for people with advanced clear cell kidney cancer that has a specific protein (CAIX). The goal is to see if the combination is safe and can shrink tumors. About 9 participan…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 11:32 UTC
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Gut bacteria boost may help kidney cancer drugs work better
Disease control OngoingThis early-phase study looks at whether adding a probiotic called CBM588 to the usual two-drug treatment (cabozantinib and nivolumab) can improve outcomes for people with advanced kidney cancer that has spread. The probiotic is meant to increase helpful gut bacteria, which may he…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 11:26 UTC
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New immunotherapy combo aims to shrink kidney tumors
Disease control TerminatedThis study tests a new combination of two immunotherapy drugs (botensilimab and balstilimab) against a standard combination (ipilimumab and nivolumab) in people with advanced kidney cancer that has spread. About 120 patients who have not had prior treatment will be randomly assig…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Michael B. Atkins, MD • Aim: Disease control
Last updated May 26, 2026 11:22 UTC
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Could a radioactive drug plus standard therapy ease bone pain in advanced kidney cancer?
Disease control OngoingThis study tests whether adding a radioactive drug (radium-223) to the usual treatment (cabozantinib) helps people with advanced kidney cancer that has spread to the bones. About 134 adults with any type of kidney cancer and bone metastases will be randomly assigned to receive ca…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New combo therapy shows promise for HIV patients with advanced cancer
Disease control OngoingThis early-phase trial is testing the safety of combining two cancer drugs—nivolumab and cabozantinib—in people with HIV who have advanced solid tumors. The study includes 8 participants with various cancers that have spread. The goal is to see if the combination can shrink or st…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Scientists hunt for clues in tumors to match patients with the right cancer drugs
Knowledge-focused OngoingThis study collects tissue and blood samples from 156 people with advanced prostate, kidney, or bladder cancer to find genetic markers that predict how well different treatments will work. Participants give a biopsy of a growing tumor before starting their planned therapy, which …
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 11:34 UTC
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Kidney cancer drug combo under the microscope: how do patients really tolerate it?
Knowledge-focused OngoingThis study watches how adults with advanced kidney cancer handle the drugs cabozantinib (alone or with nivolumab) as their first treatment. It does not test new treatments but tracks real-life side effects, dose changes, and treatment stops. The goal is to learn how these drugs a…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Sponsor: Ipsen • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC