ADVANCED OVARIAN CARCINOMA

This study tests if a less invasive surgery (laparoscopy) works as well as standard open surgery for people with advanced ovarian, fallopian tube, or peritoneal cancer who have already had chemotherapy. About 580 participants will be randomly assigned to one of the two surgeries.…

This early-phase study tests a wearable device that creates low-intensity electric fields to disrupt cancer cell growth, combined with standard drugs (cabozantinib or nab-paclitaxel plus atezolizumab). About 43 adults with advanced solid tumors in the abdomen or chest that have s…

This early-phase study tests a new daily pill, NKT3964, that breaks down a protein called CDK2 to slow cancer growth. It is for adults with advanced solid tumors (like ovarian, endometrial, breast, gastric, or lung cancer) that have not responded to standard treatments. The study…

This study tests a vaccine made from a patient's own white blood cells, designed to train the immune system to attack ovarian cancer cells. It is for people with advanced stage III or IV ovarian, fallopian tube, or primary peritoneal cancer. The goal is to see if the vaccine can …

This study compares giving cancer treatment at home versus in a clinic for people with advanced cancers. The goal is to see if home treatment reduces stress, financial burden, and improves the overall experience. About 220 participants will be randomly assigned to receive their t…

This study tests whether taking probiotics can improve gut and vaginal health in 161 women with advanced or recurrent ovarian cancer who are receiving platinum chemotherapy. Participants will take either a probiotic or a placebo pill. Researchers will check stool and vaginal samp…

This study tests a telehealth program called REVITALIZE to see if it can lessen how much fatigue interferes with daily life for people with advanced ovarian cancer who are taking PARP inhibitors. About 240 adults will be randomly assigned to either the REVITALIZE program or recei…