ADVANCED BREAST CARCINOMA

This study is testing two new drug combinations for people with advanced breast cancer linked to BRCA gene mutations, whose cancer has started growing again despite taking standard PARP inhibitor drugs. It aims to see if adding a second drug to olaparib can shrink tumors and cont…

This study is for people with a specific type of advanced breast cancer that has spread or returned. It compares a newer targeted drug (trastuzumab deruxtecan) against a standard combination of hormone therapy and a CDK4/6 inhibitor pill. The main goal is to see which treatment i…

This early-stage trial is testing the safety of combining a wearable device that uses electric fields to disrupt cancer cells with different drug combinations. It is for adults with advanced cancers in the abdomen or chest that have spread and who have run out of standard treatme…

This study is testing whether giving standard cancer treatments at home is as safe and effective as giving them in a clinic. It aims to see if receiving care at home reduces stress, improves quality of life, and is preferred by patients with advanced cancers. About 220 participan…

This early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced solid tumors that have a specific marker called HER2. The treatment pairs an existing targeted cancer drug with a new pill that aims to block cancer cells' ability to…

This study aims to understand the experiences and support needs of people living with advanced breast cancer. Researchers will survey and interview 50 patients and caregivers to learn what has helped them, what has been difficult, and what kind of help they still need. The goal i…