ADULT SOLID NEOPLASM
Clinical trials for ADULT SOLID NEOPLASM explained in plain language.
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Experimental drug cocktail targets Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests a combination of two targeted drugs (vismodegib and erlotinib) with or without standard chemotherapy (gemcitabine) in people with advanced pancreatic cancer or other solid tumors that cannot be removed by surgery. The main goal is to find the safest d…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 12:09 UTC
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New combo therapy aims to boost immune attack on Hard-to-Treat cancers
Disease control OngoingThis early-stage study tests a new cancer vaccine (p53MVA) combined with the immunotherapy drug pembrolizumab in people with advanced solid tumors that have not responded to other treatments. The vaccine helps the immune system recognize and attack cancer cells, while pembrolizum…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 12:04 UTC
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Experimental combo targets tough cancers in early trial
Disease control OngoingThis early-phase trial tested a combination of two drugs, erlotinib and irinotecan, in 60 adults with advanced solid tumors that had stopped responding to standard treatments. The main goal was to find the safest dose and understand how the drugs work together. The study focused …
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 12:04 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis early-phase study tested the safety and best dose of two chemotherapy drugs, ixabepilone and temsirolimus, given together. It involved 22 adults with solid tumors that had spread or could not be surgically removed, and who had limited treatment options. The goal was to find …
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
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Could a drug combo shrink tough tumors? early trial underway
Disease control OngoingThis early-phase study tests two different doses of vorinostat combined with standard chemotherapy drugs (carboplatin or paclitaxel) in 20 adults with advanced solid tumors that have not responded to other treatments. The goal is to find safe dose levels and understand how the dr…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 18, 2026 12:02 UTC