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Experimental drug cocktail targets Hard-to-Treat cancers

NCT ID NCT00878163

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 24 times

Summary

This early-phase study tests a combination of two targeted drugs (vismodegib and erlotinib) with or without standard chemotherapy (gemcitabine) in people with advanced pancreatic cancer or other solid tumors that cannot be removed by surgery. The main goal is to find the safest dose and understand side effects. About 55 adults with these cancers are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

Conditions

Explore the condition pages connected to this study.