Adenocarcinoma of the rectum
Clinical trials for Adenocarcinoma of the rectum explained in plain language.
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Immunotherapy before surgery shows promise for certain colorectal cancers
Disease control OngoingThis trial is testing whether giving the immunotherapy drug pembrolizumab before surgery can improve outcomes for people with high-risk stage 2 or stage 3 colorectal cancer that has a specific genetic feature called mismatch repair deficiency. About 88 participants will receive p…
Matched conditions: ADENOCARCINOMA OF THE RECTUM
Phase 2 • Sponsor: University College, London • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Can early rectal cancer be treated without removing the rectum?
Disease control OngoingThis trial investigates whether less invasive treatments can save the rectum in people with early-stage rectal cancer. Participants receive either standard surgery (removing part of the rectum) or one of two organ-sparing approaches: short-course radiotherapy or chemoradiation (c…
Matched conditions: ADENOCARCINOMA OF THE RECTUM
Phase 2/3 • Sponsor: University of Birmingham • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC