Acute exacerbation of chronic obstructive pulmonary disease
Clinical trials for Acute exacerbation of chronic obstructive pulmonary disease explained in plain language.
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Can a blood filter ease breathing in severe COPD without a tube?
Disease control Not yet recruitingThis trial asks whether adding a device that removes carbon dioxide directly from the blood (ECCO2R) to standard noninvasive ventilation can help adults hospitalized with a severe COPD flare-up. Participants have high CO2 and acidic blood despite ventilation and cannot have a bre…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Hospital del Mar Research Institute (IMIM) • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Could a Once-Daily inhaler replace four daily doses for COPD attacks?
Disease control Not yet recruitingThis trial compares two long-acting bronchodilators (formoterol and revefenacin) against the standard short-acting combination (albuterol and ipratropium) for people hospitalized with a COPD flare-up. The goal is to see whether the longer-acting drugs can relieve shortness of bre…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Phase 4 • Sponsor: University of Tennessee Graduate School of Medicine • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New clinic aims to cut COPD Flare-Ups in half
Disease control Not yet recruitingThis study tests whether a dedicated clinic for COPD flare-ups can reduce the number of future attacks and improve quality of life. About 240 people who recently had a severe COPD attack will be split into two groups: one gets follow-up at the special clinic, the other gets stand…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Tel-Aviv Sourasky Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Ancient herbal remedy tested for Flu-Triggered lung attacks in seniors
Symptom relief Not yet recruitingThis study looks at whether a traditional Chinese herbal drink (Xuanfei Jiangzhuo Decoction) can help older adults (60+) recover faster from a COPD flare-up caused by the flu. About 300 participants will either take the herbal drink plus standard flu medicine or standard flu medi…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Tianjin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Could a simple ultrasound predict ventilator success in elderly COPD patients?
Knowledge-focused Not yet recruitingThis study looks at elderly patients (60 and older) with COPD who need a breathing machine in the ICU. Researchers will check their nutritional status and measure the thickness of their diaphragm muscle using ultrasound. The goal is to see if these factors can predict how well pa…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Can a simple blood test predict COPD Flare-Up severity?
Knowledge-focused Not yet recruitingThis study tracks people over 40 hospitalized for a COPD flare-up to see how many have a type called eosinophilic COPD, marked by higher levels of certain white blood cells. Researchers will compare hospital stay length and need for breathing support between those with and withou…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Routine blood test may reveal hidden clues in COPD emergencies
Knowledge-focused Not yet recruitingThis study looks at whether standard blood tests can help doctors predict the outcome of a sudden worsening of COPD, known as an acute exacerbation. Researchers will examine red blood cell and platelet measurements from routine blood work in 50 hospitalized adults. The goal is to…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Researchers dig into records to see how breathing help is picked for COPD Flare-Ups
Knowledge-focused Not yet recruitingThis study looks back at the hospital records of 1,000 patients with a sudden worsening of COPD (called an acute exacerbation). The goal is to see how doctors choose and change breathing support—like oxygen masks, high-flow nasal cannulas, or ventilators—during a hospital stay. N…
Matched conditions: ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sponsor: Sir Run Run Shaw Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC