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Researchers dig into records to see how breathing help is picked for COPD Flare-Ups

NCT ID NCT07508943

Knowledge-focused Sponsor: Sir Run Run Shaw Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks back at the hospital records of 1,000 patients with a sudden worsening of COPD (called an acute exacerbation). The goal is to see how doctors choose and change breathing support—like oxygen masks, high-flow nasal cannulas, or ventilators—during a hospital stay. No new treatments are given; the study only observes what happened in real-world care. The findings may help improve future decision-making for respiratory support.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will be selected retrospectively from hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease . The source population includes patients receiving routine inpatient care, with particular relevance to critically ill patients with high-quality intensive care data. Eligible participants will be identified from hospital clinical information systems and electronic medical records based on diagnosis, respiratory support records, and availability of dynamic clinical data collected during hospitalization.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Hospitalized patients with a documented diagnosis of acute exacerbation of chronic obstructive pulmonary disease. * Patients identified retrospectively from hospital records during the predefined study period. * Patients who received at least one form of respiratory support during the index hospitalization, including conventional oxygen therapy, high-flow nasal cannula oxygen therapy, noninvasive ventilation, or invasive mechanical ventilation. * Patients with available clinical records containing sufficient dynamic physiological, laboratory, and treatment-related data for retrospective analysis. Exclusion Criteria: • Patients whose hospitalization was not primarily due to acute exacerbation of COPD, even if COPD was documented as a comorbidity. Patients with stable COPD and no evidence of acute exacerbation during the index hospitalization. * Patients admitted primarily for other acute conditions, including but not limited to pneumonia without documented AECOPD, acute heart failure, pulmonary embolism, pneumothorax, asthma exacerbation, trauma, or postoperative care. * Patients with insufficient documentation to confirm AECOPD as the primary reason for admission. * Patients with incomplete clinical records preventing retrospective analysis. * Repeated hospitalizations of the same patient during the study period, with only the first eligible admission included.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute exacerbation of chronic obstructive pulmonary disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sir Run Run Shaw Hospital Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310016, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.