ABDOMINAL AORTIC ANEURYSM

This study tests a single-dose treatment delivered through a catheter to stabilize small to mid-sized abdominal aortic aneurysms (AAA) in 400 adults aged 21-85. The treatment is compared to standard monitoring. The goal is to prevent AAA-related death, rupture, or need for surger…

This early study tests a new device (Cygnum) used alongside standard surgery to repair abdominal aortic aneurysms. The goal is to see if it is safe and can prevent leaks inside the aneurysm sac after repair. About 15 adults with large aneurysms will receive the device and be foll…

This study tests whether doctor-modified grafts can safely repair complex aortic aneurysms in patients who are too high-risk for standard surgery. About 220 participants with abdominal or thoracoabdominal aneurysms or aortic dissections will receive the custom graft. The goal is …

This study compares two ways to treat complex abdominal aortic aneurysms: using a custom-made stent-graft versus one shaped with the help of a 3D-printed model of the patient's aorta. About 100 adults with large or fast-growing aneurysms will take part. The goal is to see if the …

This study is a worldwide registry that will follow 1,000 people who receive a Terumo aortic graft to repair an aneurysm in the chest or abdomen. The goal is to see how well the grafts work and how safe they are over time. Participants will be monitored for complications and surv…

This study is tracking how well a new device called the PERCUTEK Tycheseal™ stent-graft works for people with an abdominal aortic aneurysm (a bulging blood vessel in the belly). Researchers will collect data from up to 200 patients in Italy and Poland to see if the device is safe…

This study compares two medical devices (Endurant and Excluder stent grafts) used to treat abdominal aortic aneurysms—a bulging blood vessel in the belly. About 600 people with large aneurysms will be randomly assigned to receive one of the two devices. The main goal is to see wh…

This study compares two ways to screen men at high risk for abdominal aortic aneurysm (AAA): having their general practitioner use a small, portable ultrasound device during a regular visit versus the current standard of referring them to a radiologist. The goal is to see if the …

This study tests whether placing metal coils inside the aneurysm sac during standard stent-graft repair can prevent type II endoleaks—a common leak that can cause the aneurysm to grow or rupture. About 100 people with large abdominal aortic aneurysms who are at high risk for this…

This early-phase study tests a new radioactive tracer called [64Cu]-RYM2 to see if it can safely and accurately detect enzyme activity in abdominal aortic aneurysms (AAA). About 28 healthy volunteers and AAA patients will receive the tracer and undergo PET/CT scans. The goal is t…

This study at Mayo Clinic aims to test two new imaging methods to measure the strength and movement of the aorta, the body's main artery. Researchers will compare results from 30 people with and without an abdominal aortic aneurysm. The goal is to better understand how the aorta …