Vertebral column disorder

This study looks at whether giving people with PTSD a personalized mix of gut bacteria (called pharmabiotics) can help their mental health. The researchers will track changes in PTSD symptoms, anxiety, depression, and thinking skills over 14 days. The goal is to see if fixing the…

This study tests whether a special clot made from a patient's own bone marrow can help spine bones heal together faster and more reliably after spinal fusion surgery. The trial involves 96 adults with degenerative spine disease. Half will receive the standard bone graft, and the …

This study tests a spine surgery for 20 teenagers (ages 12-21) with a specific type of scoliosis called Lenke 1. The goal is to correct the spine curve and improve quality of life. Researchers will measure how well the surgery works using X-rays and patient questionnaires.

This study tests whether taking essential amino acid supplements before and after spinal surgery helps adults with spinal deformity recover better. Twenty participants will take either the supplement or a placebo for two weeks before surgery and three months after. Researchers wi…

This study tests a highly precise radiation system (CT-on-Rails or Trilogy) to treat spine tumors that have spread from other cancers. About 150 participants will receive three radiation sessions over two weeks. Researchers will track pain relief and side effects using patient qu…

This observational study follows adults with morbid obesity who undergo bariatric surgery to see how substantial weight loss affects the alignment of the spine and pelvis. Researchers measure spinal and pelvic positions on X-rays before surgery and again at 3, 6, and 12 months af…

Researchers are reviewing past spinal fusion surgeries to see if patient-specific guides, called MySpine, place screws safely even in the most challenging bone. They will compare nerve irritation rates between standard screws and those in anatomically complex positions, known as …

This study collects spinal tissue from 300 children and adults during routine spine surgery. Researchers will analyze the tissue to understand the molecular causes of spine deformity and degeneration. The goal is to identify targets for future treatments.

This study is a registry that collects medical records, quality-of-life questionnaires, and tissue samples from 900 people with spine tumors or other spine disorders. The goal is to learn more about these conditions to guide better treatment in the future. Participants must be be…

This study was designed to test a new tool that helps surgeons measure and adjust the spine during fusion surgery. The goal was to see if using the tool leads to better spinal alignment and improved patient outcomes, such as less disability. However, the study was withdrawn befor…

This study aims to develop a new way to measure how the spine moves during walking in children, both healthy and those with scoliosis. Researchers will use a special camera system and reflective markers placed on the skin to track movement. The goal is to create a reliable and ea…

This study looks at whether lying on your side or sitting upright gives a better view of the spine using ultrasound in people with a BMI over 30. Researchers will also compare two different ultrasound techniques and check how reliable the measurements are when done by doctors wit…