Varicose disease
MONDO:0008638A vascular disease characterized by the presence of enlarged and tortuous veins.
Also known as: varix, varices, varicose veins
180 clinical trials for this condition and its sub-types, 40 tagged with Varicose disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Varicose disease
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Pelvic varices 1 trial · 86 incl. sub-types
3 sub-types
- Hemorrhoid 69 trials · 72 incl. sub-types Sub-types →
- Varicocele 15 trials
- Vulval varices 0 trials
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Esophageal varices 34 trials · 55 incl. sub-types
2 sub-types
- Esophageal varices with bleeding 29 trials
- Esophageal varices without bleeding 0 trials
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Mesenteric varices 0 trials
Most studied deeper sub-types
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New trial aims to stop stomach bleeding before it starts
Disease control Not yet recruitingThis study tests whether treating enlarged stomach veins (gastric varices) early with a procedure called retrograde transvenous obliteration (RTO) can prevent dangerous bleeding. 68 adults with cirrhosis and gastric varices will be randomly assigned to either RTO or standard care…
Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Varicose vein laser treatment moves out of the OR
Symptom relief Not yet recruitingThis study will test a new way to treat varicose veins using a 1940nm laser, performed outside the operating room under local anesthesia. Researchers want to see how satisfied patients are with the procedure and check its safety and effectiveness. About 155 adults with saphenous …
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
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VR headsets could replace pills for surgery anxiety
Symptom relief Not yet recruitingThis study tests whether using virtual reality (VR) for mindfulness can help people feel less anxious and experience less pain during minor vascular surgery done under local anesthesia. 160 adults with varicose veins will be randomly assigned to either wear VR glasses with guided…
Sponsor: Tongji Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Varicose vein study: is it better to treat branch veins now or later?
Symptom relief Not yet recruitingThis study looks at the best way to treat varicose veins in the legs. It compares doing everything in one procedure versus treating the main vein first and the branch veins later. About 206 people will take part, and researchers will track how many need repeat treatment, costs, a…
Sponsor: Sir Run Run Shaw Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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New study tests pill to ease pain after varicose vein procedure
Symptom relief Not yet recruitingThis study tests whether taking calcium dobesilate before and after radiofrequency ablation for varicose veins can reduce pain and improve quality of life. 250 adults with symptomatic varicose veins will be randomly assigned to receive the drug or standard care. The main goal is …
Phase 4 • Sponsor: Oguz Arslanturk • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Does adding epinephrine improve spider vein treatment?
Symptom relief Not yet recruitingThis study tests whether adding epinephrine to a glycerin and lidocaine mixture improves the treatment of small leg veins (telangiectasias). Twenty adults will have one leg treated with the standard mixture and the other with the mixture plus epinephrine. Doctors will rate vein c…
Phase 4 • Sponsor: Goldman, Butterwick, Fitzpatrick and Groff • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Varicose vein treatment may ease knee pain in seniors
Symptom relief Not yet recruitingThis study looks at whether a common procedure for varicose veins—called endovenous ablation—can also reduce knee pain in people aged 80 and older. The researchers will follow 50 participants for one year after treatment, measuring pain and knee function. The goal is to see if im…
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Blood thinners after varicose vein surgery: safe or risky? new study investigates
Knowledge-focused Not yet recruitingThis study looks at 40 people who take blood thinners (like aspirin or warfarin) and undergo radiofrequency ablation for varicose veins. Researchers will compare bleeding risks and vein closure rates over 6 months between those on blood thinners and those not. The goal is to see …
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Vein fix may ease aching knees, new study hints
Knowledge-focused Not yet recruitingThis study will follow 50 adults with varicose veins and chronic knee pain who are scheduled for standard vein treatment (laser or radiofrequency ablation). Researchers will measure changes in knee pain, stiffness, and function before and after the procedure. The goal is to see i…
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:09 UTC