Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New study tests pill to ease pain after varicose vein procedure

NCT ID NCT07390097

Symptom relief Sponsor: Oguz Arslanturk Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking calcium dobesilate before and after radiofrequency ablation for varicose veins can reduce pain and improve quality of life. 250 adults with symptomatic varicose veins will be randomly assigned to receive the drug or standard care. The main goal is to measure pain levels one week after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
calcium dobesilate
What this could lead to
If it works, this could point toward a simple pill to ease pain and speed up recovery after varicose vein treatment.
What could go wrong
This is a Phase 4 trial, but it's still early and small. The drug may not reduce pain more than standard care, and side effects like stomach upset are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-70 years * Symptomatic primary varicose veins (CEAP classification C2-C4) * Great saphenous vein insufficiency confirmed by duplex ultrasound (reflux \>0.5 seconds) * Great saphenous vein diameter 5-12 mm * Scheduled for radiofrequency ablation * Able to provide written informed consent Exclusion Criteria: * History of deep vein thrombosis * Peripheral arterial disease (ABI \<0.9) * Active venous ulcer (CEAP C6) * Pregnancy or breastfeeding * Severe renal or hepatic insufficiency * Known allergy to calcium dobesilate * Use of venoactive drugs within the past 4 weeks * Current anticoagulant therapy * Previous venous intervention on the same limb * Bilateral disease requiring simultaneous treatment * Inability to comply with follow-up schedule

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chronic venous insufficiency are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

chronic venous insufficiency Pain, Postoperative varicose disease venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic venous insufficiency Great saphenous vein insufficiency Varicose veins leg

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Zonguldak Bulent Ecevit University Hospital, Department of Cardiovascular Surgery

    Kozlu, Zonguldak Province, 67600, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.