Urticaria
MONDO:0005492A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.
Also known as: hives, urticaria, urticaria (disease), Urticarias
165 clinical trials for this condition and its sub-types, 28 tagged with Urticaria itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Urticaria
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Angioedema 19 trials · 66 incl. sub-types
3 sub-types
- Hereditary angioedema 58 trials · 60 incl. sub-types Sub-types →
- Acquired angioedema 2 trials · 3 incl. sub-types Sub-types →
- Non-histaminic angioedema 2 trials
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Idiopathic urticaria 0 trials · 66 incl. sub-types
2 sub-types
- Chronic idiopathic urticaria 65 trials
- Acute idiopathic urticaria 1 trial
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Chronic urticaria 12 trials · 20 incl. sub-types
1 sub-type
- Chronic inducible urticaria 8 trials
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Physical urticaria 3 trials · 15 incl. sub-types
3 sub-types
- Familial dermatographia 12 trials
- Cholinergic urticaria 2 trials
- Vibratory urticaria 0 trials · 2 incl. sub-types Sub-types →
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Cold urticaria 10 trials
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Allergic urticaria 3 trials · 5 incl. sub-types
1 sub-type
- Non-histaminic angioedema 2 trials
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Cutaneous mastocytosis 1 trial
3 sub-types
- Cutaneous mastocytoma 0 trials Sub-types →
- Diffuse cutaneous mastocytosis 0 trials Sub-types →
- Maculopapular cutaneous mastocytosis 0 trials Sub-types →
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Urticaria, aquagenic 1 trial
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Melkersson-Rosenthal syndrome 0 trials
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Autoimmune urticaria 0 trials
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Papular urticaria 0 trials
Most studied deeper sub-types
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Can a new pill silence stubborn hives?
Disease control Not yet recruitingThis trial is testing an experimental oral medication called THB335 in adults with chronic spontaneous urticaria (CSU), a condition marked by persistent hives and itching that standard antihistamines don't fully control. Participants will take THB335 or a placebo alongside their …
Phase 2 • Sponsor: Calixis Inc. • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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AI tool aims to cut allergy misdiagnosis in primary care
Diagnosis Not yet recruitingThis study tests whether AI-powered decision trees can help general practitioners better diagnose and manage allergies. About 600 patients with suspected allergies will be enrolled, and doctors will use an app that suggests next steps based on symptoms. The goal is to see if this…
Sponsor: University Hospital, Montpellier • Aim: Diagnosis
Last updated Jun 27, 2026 13:02 UTC
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New gel promises Ultra-Fast itch relief in seconds
Symptom relief Not yet recruitingThis study tests a gel made from hyaluronan (HA35) to see if it can quickly relieve moderate-to-severe itching from conditions like eczema, insect bites, and hives. About 30 adults will apply the gel once, and researchers will check itch levels at several time points up to 24 hou…
Sponsor: Nakhia Impex LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Ear seeds and allergy pills: a new combo for hives?
Symptom relief Not yet recruitingThis study tests whether adding ear acupressure (using tiny seed patches on specific ear points) to a standard antihistamine (Loratadine) can better reduce hives symptoms and improve quality of life compared to a sham ear treatment. Sixty-six adults with Wind-Heat type urticaria …
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Dermatology study aims to cut unnecessary clinic visits with simple surveys
Knowledge-focused Not yet recruitingThis study tests whether letting patients report their symptoms online can help doctors schedule follow-up visits only when needed. About 250 adults with chronic skin conditions like eczema or psoriasis will either get standard fixed appointments or flexible scheduling based on m…
Sponsor: National University Hospital, Singapore • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Eye scans could reveal hidden skin disease risk
Knowledge-focused Not yet recruitingThis study will take high-resolution photos of the eyes of 950 people with psoriasis, eczema, or hives, plus healthy volunteers. Using artificial intelligence, researchers aim to find eye patterns linked to these skin conditions. The goal is to create a noninvasive tool for earli…
Sponsor: Shanghai Yueyang Integrated Medicine Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC