Urinary system disorder
MONDO:0002118A disease involving the renal system.
Also known as: disease of renal system, disease or disorder of renal system, disease, urinary tract, disease, urologic, disease, urological, diseases, urinary tract, diseases, urologic, diseases, urological
5523 clinical trials for this condition and its sub-types, 72 tagged with Urinary system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Urinary system disorder
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Kidney disorder 223 trials · 4,032 incl. sub-types
57 sub-types
- Chronic kidney disease 1,091 trials · 1,566 incl. sub-types Sub-types →
- Kidney failure 236 trials · 1,389 incl. sub-types Sub-types →
- Kidney neoplasm 59 trials · 860 incl. sub-types Sub-types →
- Nephritis 16 trials · 503 incl. sub-types Sub-types →
- Glomerular disorder 9 trials · 481 incl. sub-types Sub-types →
- Inherited kidney disorder 1 trial · 317 incl. sub-types Sub-types →
- Nephrolithiasis 252 trials · 254 incl. sub-types Sub-types →
- Proteinuria 65 trials · 137 incl. sub-types Sub-types →
- Impaired renal function disease 109 trials · 129 incl. sub-types Sub-types →
- Cystic kidney disease 8 trials · 87 incl. sub-types Sub-types →
- Nephrosis 0 trials · 71 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Renal tubule disorder 1 trial · 47 incl. sub-types Sub-types →
- Diabetes insipidus 33 trials · 37 incl. sub-types Sub-types →
- Renal tubular transport disease 0 trials · 17 incl. sub-types Sub-types →
- Hydronephrosis 7 trials · 9 incl. sub-types Sub-types →
- Stricture or kinking of ureter 9 trials
- Hypertensive nephropathy 8 trials Sub-types →
- Nephrocalcinosis 7 trials · 8 incl. sub-types Sub-types →
- Renal artery disease 3 trials · 7 incl. sub-types Sub-types →
- Fetal lower urinary tract obstruction 0 trials · 6 incl. sub-types Sub-types →
- Congenital primary megaureter 5 trials Sub-types →
- Renal hypertension 0 trials · 4 incl. sub-types Sub-types →
- Distal renal tubular acidosis 3 trials Sub-types →
- Exstrophy-epispadias complex 1 trial · 3 incl. sub-types Sub-types →
- Acute tubulointerstitial nephritis 2 trials
- Kidney cortex necrosis 2 trials
- IgG4-related kidney disease 1 trial
- Anuria 1 trial
- Crush syndrome 1 trial
- Obstructive nephropathy 1 trial
- Orthostatic proteinuria 1 trial
- Renal hypoplasia 1 trial Sub-types →
- Renal nutcracker syndrome 1 trial
- Arnold stickler bourne syndrome 0 trials
- C1q nephropathy 0 trials
- X-linked diffuse leiomyomatosis-Alport syndrome 0 trials Sub-types →
- Atheroembolism of kidney 0 trials
- Atypical Fanconi syndrome-neonatal hyperinsulinism syndrome 0 trials
- Autosomal dominant progressive nephropathy with hypertension 0 trials
- Congenital megacalycosis 0 trials Sub-types →
- Congenital renal artery stenosis 0 trials
- Duplication of urethra 0 trials
- Idiopathic non-lupus full-house nephropathy 0 trials
- Kidney cortex disease 0 trials
- Kidney hypertrophy 0 trials
- Kidney papillary necrosis 0 trials Sub-types →
- Lachiewicz sibley syndrome 0 trials
- Neonatal renal venous thrombosis 0 trials
- Non-syndromic supernumerary kidneys 0 trials
- Oligomeganephronia 0 trials
- Perinephritis 0 trials
- Pyonephrosis 0 trials
- Renal aminoaciduria 0 trials
- Renal dysplasia 0 trials Sub-types →
- Renal tubular dysgenesis 0 trials Sub-types →
- Tubulointerstitial nephritis and uveitis syndrome 0 trials
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Urinary system neoplasm 21 trials · 1,690 incl. sub-types
8 sub-types
- Malignant urinary system neoplasm 75 trials · 1,664 incl. sub-types Sub-types →
- Kidney neoplasm 59 trials · 860 incl. sub-types Sub-types →
- Urinary bladder neoplasm 65 trials · 699 incl. sub-types Sub-types →
- Urothelial neoplasm 2 trials · 693 incl. sub-types Sub-types →
- Benign urinary system neoplasm 50 trials · 62 incl. sub-types Sub-types →
- Ureter neoplasm 2 trials · 34 incl. sub-types Sub-types →
- Urethra neoplasm 3 trials · 31 incl. sub-types Sub-types →
- Prostate phyllodes tumor 0 trials Sub-types →
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Urinary bladder disorder 24 trials · 1,152 incl. sub-types
17 sub-types
- Urinary bladder neoplasm 65 trials · 699 incl. sub-types Sub-types →
- Overactive bladder 168 trials
- Female stress incontinence 137 trials
- Cystitis 12 trials · 72 incl. sub-types Sub-types →
- Ureterolithiasis 49 trials
- Bladder neck obstruction 12 trials
- Hinman syndrome 5 trials
- Bladder calculus 5 trials Sub-types →
- Vesicoureteral reflux 5 trials Sub-types →
- Detrusor sphincter dyssynergia 3 trials
- Urinary schistosomiasis 3 trials
- Low compliance bladder 2 trials
- Postcholecystectomy syndrome 1 trial
- Bladder diverticulum 0 trials Sub-types →
- Disorder of neck of urinary bladder 0 trials Sub-types →
- Ureterocele 0 trials
- Urinary bladder tuberculosis 0 trials
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Urolithiasis 119 trials · 312 incl. sub-types
2 sub-types
- Nephrolithiasis 252 trials · 254 incl. sub-types Sub-types →
- Lower urinary tract calculus 0 trials · 5 incl. sub-types Sub-types →
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Urinary tract infection 156 trials · 250 incl. sub-types
5 sub-types
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
- Urinary schistosomiasis 3 trials
- Pyoureter 0 trials
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Ureteral disorder 2 trials · 95 incl. sub-types
8 sub-types
- Ureterolithiasis 49 trials
- Ureter neoplasm 2 trials · 34 incl. sub-types Sub-types →
- Ureteral obstruction 9 trials
- Vesicoureteral reflux 5 trials Sub-types →
- Pyoureter 0 trials
- Ureter tuberculosis 0 trials
- Ureteritis 0 trials
- Ureterocele 0 trials
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Urethral disorder 1 trial · 70 incl. sub-types
10 sub-types
- Urethra neoplasm 3 trials · 31 incl. sub-types Sub-types →
- Urethral obstruction 3 trials · 26 incl. sub-types Sub-types →
- Urethritis 5 trials · 6 incl. sub-types Sub-types →
- Urethral syndrome 4 trials
- Urethral intrinsic sphincter deficiency 3 trials
- Fibroepithelial polyp of urethra 0 trials
- Prolapse of urethra 0 trials
- Urethral calculus 0 trials
- Urethral false passage 0 trials
- Urethral gland abscess 0 trials
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Urinary tract obstruction 12 trials · 27 incl. sub-types
2 sub-types
- Hydronephrosis 7 trials · 9 incl. sub-types Sub-types →
- Ureteral obstruction 9 trials
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Bacteriuria 11 trials
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Idiopathic hypercalciuria 3 trials
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Paraneoplastic renal syndrome 0 trials · 3 incl. sub-types
1 sub-type
- Oncogenic osteomalacia 3 trials
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Congenital urachal anomaly 0 trials
4 sub-types
- Patent urachus 0 trials
- Urachal cyst 0 trials
- Urachal diverticulum 0 trials
- Urachal sinus 0 trials
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Hypercalciuria, absorptive, 1 0 trials
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Hypercalciuria, absorptive, 2 0 trials
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Hyperglycinuria 0 trials
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Megacystis-megaureter syndrome 0 trials
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Meningitis-retention syndrome 0 trials
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Postorgasmic illness syndrome 0 trials
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Pyuria 0 trials
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Urothelial hyperplasia 0 trials
2 sub-types
- Flat urothelial hyperplasia 0 trials
- Papillary urothelial hyperplasia 0 trials
Most studied deeper sub-types
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New drug BHV-1400 aims to protect kidneys in IgA nephropathy
Disease control Not yet recruitingThis Phase 3 trial tests whether BHV-1400 can safely reduce protein in the urine and preserve kidney function in 420 adults with IgA nephropathy. Participants are randomly assigned to receive either the drug or a placebo by injection. The main goal is to see if BHV-1400 lowers pr…
Phase 3 • Sponsor: Biohaven Therapeutics Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Scientists grow penile tissue in lab for first human trial
Disease control Not yet recruitingThis early-stage trial tests a lab-grown penile tissue made from a man's own cells to repair severe, irreversible damage to the penis. Ten men aged 18-60 who have failed standard treatments will receive the implant. The main goal is to check safety, not effectiveness.
Phase 1 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Could skipping antibiotics before bladder botox be safe? new trial aims to find out
Disease control Not yet recruitingThis study looks at whether it is safe to avoid antibiotics before bladder Botox injections in people with multiple sclerosis or spinal cord injury who have bacteria in their urine but no symptoms. About 526 participants will be randomly assigned to receive either antibiotics or …
Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Ancient herb takes on modern kidney damage
Disease control Not yet recruitingThis study tests Shenkangling, a traditional Chinese herbal tonic, in 100 adults who experience kidney injury during surgery. The goal is to see if it helps kidneys recover and is safe. Participants take the herb twice daily, and researchers measure urine and blood markers of kid…
Phase 4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 26, 2026 13:59 UTC
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New drug duo aims to save bladders in HER2-positive cancer patients
Disease control Not yet recruitingThis phase 2 trial tests two drugs—disitamab vedotin and toripalimab—as a way to treat HER2-positive muscle-invasive bladder cancer without removing the bladder. About 60 adults with locally advanced cancer will receive different cycles of the combination. The main goal is to see…
Phase 2 • Sponsor: Renmin Hospital of Wuhan University • Aim: Disease control
Last updated Jun 26, 2026 13:16 UTC
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Ankle nerve zap may ease Kids' bladder troubles
Symptom relief Not yet recruitingThis study tests whether stimulating a nerve near the ankle, called percutaneous tibial nerve stimulation (PTNS), can safely treat overactive bladder in children aged 5 to 21. The treatment uses a device called Urgent PC that sends weak electrical signals through a thin needle to…
Phase 4 • Sponsor: Chi Dang Hornik • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Reminder calls aim to cut missed surgeries
Knowledge-focused Not yet recruitingThis study looks at whether extra phone calls and text messages can help patients who are likely to miss their urology procedures. About 68 adults at high risk of no-showing will be split into two groups: one gets standard care, the other gets extra reminders. The goal is to see …
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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New symptom diaries aim to improve daily tracking of recurrent UTIs, especially for seniors
Knowledge-focused Not yet recruitingThis study is creating and testing two new patient-reported tools to measure recurrent urinary tract infection (UTI) symptoms. One is a daily symptom diary for adults, and the other is adapted specifically for people aged 65 and older. About 200 participants with recurrent UTIs w…
Sponsor: Katherine Finlay • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC