Univentricular heart

MONDO:0015451

Univentricular heart (UVH) is a severe congenital cardiac malformation characterized by both atria related entirely or almost entirely to one functionally single ventricular chamber. The clinical manifestations include congestive heart failure, failure to thrive, cyanosis, hypoxemia and neurodevelopmental disabilities.

Also known as: Double inlet left ventricle

23 clinical trials for this condition and its sub-types, 21 tagged with Univentricular heart itself.

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Where it sits in the disease tree

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↑ Univentricular cardiopathy (37)

Sub-types of Univentricular heart

Univentricular heart with single atrio-ventricular valve 0 trials

Including sub-types (23) Tagged with Univentricular heart (21)

Trials to join now! 13 Not yet recruiting 1 Not yet finished but already full! 4 Completed 4 Terminated 1

Dopamine may unclog lymphatic system in rare heart complication

Knowledge-focused Stopped early

This study looks at whether dopamine can improve lymph flow in people who developed protein-losing enteropathy (PLE) after Fontan surgery for single-ventricle heart disease. PLE is a serious complication where proteins leak into the gut, possibly due to poor lymphatic function. R…

Sponsor: University of Michigan • Aim: Knowledge-focused

Last updated Jul 16, 2026 00:00 UTC

Univentricular heart

Where it sits in the disease tree

Dopamine may unclog lymphatic system in rare heart complication