Undifferentiated connective tissue syndrome

This study aims to find better ways to detect lung scarring (interstitial lung disease) early in people with connective tissue diseases like scleroderma or rheumatoid arthritis. Researchers will analyze tiny particles in the blood called extracellular vesicles and use AI to exami…

This study looks at whether a quick, painless test called capillaroscopy (examining tiny blood vessels at the fingernails) can help doctors diagnose specific connective tissue diseases sooner in people with an unclear autoimmune condition. About 40 adults with undifferentiated co…

This study is building a large registry and biorepository of 5,000 adults with various rheumatic diseases like rheumatoid arthritis, lupus, and scleroderma. Researchers at Yale University will collect medical data and biological samples over time to better understand these condit…

This registry follows 100 people with undifferentiated connective tissue disease (UCTD), a condition with symptoms like joint pain, rash, and fatigue that doesn't fit a specific diagnosis. Researchers will track changes in quality of life, fatigue, depression, and disease feature…

This registry enrolls pregnant women or those planning pregnancy who have autoimmune diseases like lupus or rheumatoid arthritis. Researchers at Duke University will track health data to find ways to improve outcomes for mothers and babies. The goal is to better understand risk f…