Twin to twin transfusion syndrome
MONDO:0019805Twin twin transfusion syndrome (TTTS) is a rare condition seen in twin monochorionic pregnancies, typically developing during the 15-26 week gestation period and usually due to unbalanced intertwin placental anastomoses, where an unequal exchange of blood between twins causes oligohydramnios in one sac and polyhydramnios in the other which can lead to a high perinatal mortality rate and a high rate of disability in survivors if left untreated
Also known as: Feto-fetal transfusion syndrome, Twin Anemia Polycythemia Sequence, Twin-Twin transfusion syndrome, foetal blood loss from foetal haemorrhage into co-twin, foetal haemorrhage into co-twin, placental transfusion syndrome, stuck Twin syndrome, twin-to-twin transfusion syndrome
23 clinical trials for this condition and its sub-types, 14 tagged with Twin to twin transfusion syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Twin to twin transfusion syndrome
-
Simple cord milking procedure could save preterm Infants' lives
Disease control Recruiting nowThis trial compares two ways of managing the umbilical cord right after birth in preterm infants (30-34 weeks) who are not vigorous. One method, umbilical cord milking, involves pushing blood from the cord toward the baby before clamping. The other is early cord clamping. The stu…
Sponsor: Nemours Children's Clinic • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
-
Waiting to clamp the cord: could 30 seconds save preterm babies?
Disease control Recruiting nowThis study compares delayed cord clamping (waiting at least 30 seconds after birth) with immediate clamping in preterm infants born between 32 and 37 weeks. The goal is to see if the extra time improves early health outcomes such as breathing, anemia risk, and survival. Researche…
Sponsor: Faculty of Medicine of Tunis • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
-
Cord blood boost: new study aims to help tiniest newborns
Disease control Recruiting nowThis study looks at three methods of giving premature babies (born at 32 weeks or earlier) extra blood from the placenta right after birth: intact cord milking, cut-cord milking, and delayed cord clamping. Researchers want to see which method best improves the baby's blood health…
Sponsor: Alexandria University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
-
New fetal heart monitor could unlock secrets of stillbirth
Knowledge-focused Recruiting nowThis study is testing a new, non-invasive monitor (fetal magnetocardiography) to detect hidden heart problems in high-risk pregnancies that might lead to fetal death. Researchers will study 30 pregnant women with conditions like congenital heart disease or twin pregnancy. The goa…
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
-
Twin surgery study: which entry method is safer?
Knowledge-focused Recruiting nowThis study looks at two common techniques surgeons use to enter the uterus during laser surgery for twin-to-twin transfusion syndrome. The goal is to see if one method causes less separation of the membrane around the baby. About 216 pregnant women with this condition will take p…
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
-
AI could revolutionize heart valve surgery predictions
Knowledge-focused Recruiting nowThis study uses artificial intelligence to analyze data from 21,000 patients who had heart valve procedures. The goal is to make AI tools that can predict surgery outcomes, like which device to use and risks of complications, with over 90% accuracy. This is a non-interventional s…
Sponsor: Montreal Heart Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC