Transient myeloproliferative syndrome

A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission.

Also known as: MST, TAM, TMD, Transient abnormal myelopoiesis associated with Down syndrome, leukemia, transient, of Down syndrome, transient abnormal myelopoiesis, transient leukaemia, transient leurkemia of Down syndrome

3076 clinical trials for this condition and its sub-types, 13 tagged with Transient myeloproliferative syndrome itself.