Tourette syndrome
MONDO:0007661A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen.
Also known as: Tourette disease, Tourette syndrome, Tourette's syndrome, motor-verbal tic disorder, GTS, Gilles De 50A Tourette syndrome, Gilles de la Tourette syndrome, Tourette disorder
52 clinical trials for this condition and its sub-types, 41 tagged with Tourette syndrome itself.
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Can a dopamine-blocking drug safely control tourette syndrome over years?
Disease control OngoingThis trial investigates the long-term safety of ecopipam, a drug that blocks dopamine D1 and D5 receptors, in children, adolescents, and adults with Tourette syndrome. Participants who completed a prior study may enroll and receive ecopipam for up to 24 weeks or longer. The main …
Phase 3 • Sponsor: Emalex Biosciences Inc. • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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New pill aims to quiet tourette tics in landmark trial
Symptom relief OngoingThis study tests an experimental drug called gemlapodect to see if it can safely reduce tics in people with Tourette syndrome. About 164 adults and teens with moderate to severe tics will take the drug or a placebo for 12 weeks. The main goal is to measure changes in tic severity…
Phase 2 • Sponsor: Noema Pharma AG • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Everyday therapists? study tests Non-Licensed CBT in hospitals
Symptom relief OngoingThis study looks at whether unlicensed professionals can successfully provide cognitive behavioral therapy (CBT) to patients in a general hospital. It includes 250 adults with conditions like anxiety, depression, OCD, and PTSD. The goal is to see if this approach improves psychol…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Brain scans reveal why tourette patients are hypersensitive to everyday stimuli
Knowledge-focused By invitation onlyThis study aims to understand why many people with Tourette syndrome are overly sensitive to everyday sensations like touch or noise. Researchers will monitor brain activity, heart rate, and sweat responses in 50 adults with Tourette syndrome while they experience different sound…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC