Thymus cancer

This study tests a drug called PT-112 in people with thymoma or thymic cancer that has come back or worsened after standard treatment. PT-112 is designed to kill cancer cells and boost the immune system. About 53 adults will receive the drug intravenously in 28-day cycles. The ma…

This early-phase study tests a new treatment called TNhYP218 CAR T cells for people with solid tumors that have high levels of a protein called mesothelin, including mesothelioma. Participants' own immune cells are collected, modified in a lab to better attack cancer, and then gi…

This early-phase trial is testing the safety of the immunotherapy drug pembrolizumab (Keytruda) in 37 people with thymoma or thymic carcinoma that cannot be removed by surgery. The drug helps the immune system attack cancer cells. Researchers are looking at side effects and how w…

This study is testing a precise type of radiation called IMPRINT for people whose thymic cancer has spread to the lining of the lung (pleura). The main goal is to see if this treatment is safe and causes only mild side effects, especially lung inflammation. About 36 participants …

This study aims to collect health information from 12,000 adults with lung or other chest cancers. Researchers want to understand why some people respond better to treatment than others, even when their cancer stage is the same. By gathering data from routine care, they hope to i…

This study is building a huge registry of information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. Researchers will use this resource to study what causes cancer and how to better prevent, detect, and treat it. The re…