Thrombophilia

MONDO:0002305

A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Also known as: excessive blood clotting, hypercoagulability, hypercoagulability state, hypercoagulable

78 clinical trials for this condition and its sub-types, 12 tagged with Thrombophilia itself.

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Where it sits in the disease tree

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Part of

↑ Blood coagulation disease (539)

Sub-types of Thrombophilia

Inherited thrombophilia 0 trials · 28 incl. sub-types
12 sub-types
- Thrombophilia due to thrombin defect 19 trials
- Thrombophilia due to activated protein C resistance 5 trials
- Hereditary antithrombin deficiency 3 trials
- Hereditary thrombophilia due to congenital protein C deficiency 1 trial Sub-types →
- Factor 5 excess with spontaneous thrombosis 0 trials
- Heparin cofactor 2 deficiency 0 trials
- Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency 0 trials
- Hereditary thrombophilia due to congenital protein S deficiency 0 trials Sub-types →
- Thrombomodulin-related bleeding disorder 0 trials
- Thrombophilia, X-linked, due to factor 8 defect 0 trials
- Thrombophilia, X-linked, due to factor 9 defect 0 trials
- Thrombophilia, familial, due to decreased release of tissue plasminogen activator 0 trials
Thrombotic thrombocytopenic purpura 15 trials · 20 incl. sub-types
2 sub-types
- Acquired thrombotic thrombocytopenic purpura 13 trials
- Congenital thrombotic thrombocytopenic purpura 5 trials
Disseminated intravascular coagulation 15 trials
2 sub-types
- Disseminated intravascular coagulation in newborn 0 trials
- Purpura fulminans 0 trials Sub-types →
Protein S deficiency 3 trials
1 sub-type
- Hereditary thrombophilia due to congenital protein S deficiency 0 trials Sub-types →

Most studied deeper sub-types

Acquired purpura fulminans (0) Thrombophilia due to protein C deficiency, autosomal dominant (0) Thrombophilia due to protein C deficiency, autosomal recessive (0) Thrombophilia due to protein S deficiency, autosomal dominant (0) Thrombophilia due to protein S deficiency, autosomal recessive (0)

Including sub-types (78) Tagged with Thrombophilia (12)

Trials to join now! 24 Not yet recruiting 13 Not yet finished but already full! 11 Completed 27 Terminated 3

Thrombophilia

Where it sits in the disease tree

Most studied deeper sub-types

Tailored drug regimen shows promise for rare blood disorder

Cancer drug combo shows promise for Hard-to-Treat bowel cancer

Tiny study on clotting disorder and artery health ends early