Thrombophilia
MONDO:0002305A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.
Also known as: excessive blood clotting, hypercoagulability, hypercoagulability state, hypercoagulable
78 clinical trials for this condition and its sub-types, 12 tagged with Thrombophilia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Thrombophilia
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Inherited thrombophilia 0 trials · 28 incl. sub-types
12 sub-types
- Thrombophilia due to thrombin defect 19 trials
- Thrombophilia due to activated protein C resistance 5 trials
- Hereditary antithrombin deficiency 3 trials
- Hereditary thrombophilia due to congenital protein C deficiency 1 trial Sub-types →
- Factor 5 excess with spontaneous thrombosis 0 trials
- Heparin cofactor 2 deficiency 0 trials
- Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency 0 trials
- Hereditary thrombophilia due to congenital protein S deficiency 0 trials Sub-types →
- Thrombomodulin-related bleeding disorder 0 trials
- Thrombophilia, X-linked, due to factor 8 defect 0 trials
- Thrombophilia, X-linked, due to factor 9 defect 0 trials
- Thrombophilia, familial, due to decreased release of tissue plasminogen activator 0 trials
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Thrombotic thrombocytopenic purpura 15 trials · 20 incl. sub-types
2 sub-types
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Disseminated intravascular coagulation 15 trials
2 sub-types
- Disseminated intravascular coagulation in newborn 0 trials
- Purpura fulminans 0 trials Sub-types →
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Protein S deficiency 3 trials
1 sub-type
Most studied deeper sub-types
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Could a simple aspirin pill replace daily shots to prevent postpartum blood clots?
Prevention Recruiting nowThis trial tests whether taking a low-dose aspirin pill every day for six weeks after delivery can prevent dangerous blood clots in the legs or lungs as effectively as the standard daily heparin injections. The study enrolls people who have given birth and have one or more risk f…
Phase 3 • Sponsor: University of Calgary • Aim: Prevention
Last updated Jul 29, 2026 00:00 UTC
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Massive study to track Real-World safety of new blood disorder drugs
Knowledge-focused Recruiting nowThis study is collecting long-term safety and effectiveness data on treatments for various blood disorders, including hemophilia, sickle cell disease, and clotting disorders. It aims to enroll 3000 people of any age with these conditions. Researchers will monitor side effects, co…
Sponsor: American Thrombosis and Hemostasis Network • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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New study aims to predict clot risk in PCOS patients
Knowledge-focused Recruiting nowThis study is creating a risk assessment system to predict blood clotting abnormalities in women with polycystic ovary syndrome (PCOS). Researchers will analyze hormone, metabolic, and genetic factors in 100 participants aged 14 to 45. The goal is to help doctors personalize care…
Sponsor: Guangdong Women and Children Hospital • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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New study tests safer blood thinners for Clot-Prone patients
Knowledge-focused Recruiting nowThis study looks at two types of blood thinners—direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs)—to see which works better at preventing repeat blood clots in people with a low-risk form of antiphospholipid syndrome (APS). APS is an autoimmune condition that ra…
Sponsor: Infanta Leonor University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC