Tetanus

This phase 3 trial tests a new combination vaccine called BK1803 in healthy infants aged 2 to 7 months. The vaccine aims to protect against six diseases: whooping cough, diphtheria, tetanus, polio, hepatitis B, and Haemophilus influenzae type b. Researchers compare BK1803 to a st…

This first-in-human study tests a new microneedle patch (Miracus) that dissolves in the skin to deliver a tetanus vaccine without a needle. Thirty healthy adults will receive either an empty patch or one loaded with vaccine. Researchers will check safety, tolerability, and whethe…

This study tests a new vaccine called TdaP2gen in 320 pregnant women in Thailand to see if it safely protects their babies from tetanus, diphtheria, and whooping cough. The vaccine is given during pregnancy, and researchers measure antibody levels in mothers and infants up to 18 …

This early-stage trial is testing a new combination vaccine that protects against whooping cough, diphtheria, and tetanus (Tdap) in people aged 10 and older. Researchers want to see if different doses are safe and trigger an immune response. The study involves 96 volunteers and c…

This study tests a new version of the Tdap vaccine (which protects against tetanus, diphtheria, and whooping cough) that has reduced antigens. The goal is to see if it is safe and triggers a strong immune response in people aged 6 and up. Around 660 volunteers will receive either…

Researchers are testing a new immunotherapy called Lm-LLO-TT in adults with advanced pancreatic ductal adenocarcinoma that has already been treated with chemotherapy. Lm-LLO-TT uses a weakened form of Listeria bacteria engineered to carry a tetanus toxoid antigen, aiming to spark…

This study aims to create a quick, non-invasive test using saliva to see if someone has enough antibodies to fight tetanus. Instead of drawing blood, a small saliva sample on a test strip would give results in 10-15 minutes. The test is designed for low- and middle-income areas w…

This study tests a new medicine called SNA02-48 to see if it can prevent tetanus in people who have had a high-risk wound, like a deep cut or puncture from a dirty object. About 600 adults will receive either the new injection or the standard treatment (human tetanus immunoglobul…

This study checks how long protection from a tetanus vaccine lasts. Researchers take blood samples from 240 people who received the vaccine or a control in an earlier trial, 2.5 years after their shots. They measure antibody levels to see if they still meet protective thresholds.…

This study follows 160 people who previously received a 5-component DTP vaccine (protecting against diphtheria, tetanus, and pertussis) to see how long their immune protection lasts. Blood samples are taken at 2.5, 5, and 10 years after vaccination to measure antibody levels. The…