Takayasu arteritis
MONDO:0017991A rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.
Also known as: Arteritis, Takayasu, Takayasu arteritis, Takayasu's arteritis, Takayasu's disease, aortic arch arteritis, aortic arch syndrome, cervical aortic arch, idiopathic aortitis
30 clinical trials for this condition and its sub-types, 27 tagged with Takayasu arteritis itself.
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New hope for rare artery disease? small trial tests upadacitinib
Disease control CompletedThis completed study tested the drug upadacitinib in 12 people with refractory Takayasu arteritis, a rare autoimmune disease that inflames the body's largest artery. The goal was to see if the drug could help patients who haven't responded to standard treatments achieve remission…
Sponsor: Liu Tian • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Could a tiny dose of naltrexone ease vasculitis symptoms?
Symptom relief CompletedThis study tested whether a low dose (4.5 mg) of naltrexone, a drug already used for alcoholism, can improve physical health and quality of life in people with vasculitis. Sixty participants took either the drug or a placebo daily for six weeks. The goal was to see if the drug le…
Phase 2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Rare artery disease linked to higher heart attack and stroke risk
Knowledge-focused CompletedThis study uses French national health data to compare the risk of major heart problems—like heart attack, stroke, and death—in people with Takayasu arteritis versus similar people without the disease. It also looks at how steroid use may affect these risks. The goal is to better…
Sponsor: Groupe français d'étude des Maladies Inflammatoires de loeil • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Scientists hunt for clues to diagnose rare inflammatory diseases
Knowledge-focused CompletedThis completed study reviewed the medical records of 210 people with aortitis (inflammation of the aorta) or retroperitoneal fibrosis (scar tissue in the abdomen). The goal was to find patterns in symptoms, lab tests, and imaging that could help doctors tell different types of th…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New monitoring methods aim to prevent paralysis after aortic surgery
Knowledge-focused CompletedThis study tests two new monitoring techniques—long loop reflexes (F-waves) and near-infrared spectroscopy (NIRS)—to detect spinal cord ischemia early after thoracoabdominal aortic aneurysm repair. Current methods work during surgery but are too painful for awake patients afterwa…
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Surgery may boost survival in rare artery disease
Knowledge-focused CompletedThis study looked at 78 people with Takayasu arteritis, a rare disease that causes narrowing of the main artery from the heart. Researchers compared those who had surgery or a procedure to open the artery with those who got only medication. The goal was to see which group lived l…
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:45 UTC