T-cell immunodeficiency
MONDO:0003780A broad classification of disorders that affect the cell-mediated aspect of the immune response. Circulating numbers of T lymphocytes are decreased or ineffective.
Also known as: T-cell immunodeficiency, T-lymphocyte deficiency (finding), T-lymphocyte immunodeficiency, T lymphocyte deficiency
484 clinical trials for this condition and its sub-types, 4 tagged with T-cell immunodeficiency itself.
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Sub-types of T-cell immunodeficiency
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AIDS 463 trials
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Congenital T-cell immunodeficiency 0 trials · 13 incl. sub-types
2 sub-types
- DiGeorge syndrome 11 trials
- Nezelof syndrome 2 trials
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Can a new immune system fix T-Cell diseases? trial tests donor transplants
Disease control OngoingThis study tests whether a stem cell transplant from a healthy donor can safely treat people with severe T-cell problems. Participants receive chemotherapy and antibody therapy before the transplant, followed by donor stem cells. The goal is to see if the new immune system can co…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Double transplant breakthrough offers hope for rare immune disorder patients
Disease control By invitation onlyThis study tests a new approach for people aged 5 to 45 with primary immune deficiencies and end-stage lung disease. Participants receive a double lung transplant followed by a stem cell transplant from the same donor. The goal is to see if this combined procedure is safe and can…
Phase 1/2 • Sponsor: Paul Szabolcs • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC