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Double transplant breakthrough offers new hope for kids with fatal immune diseases

NCT ID NCT01852370

ENROLLING_BY_INVITATION Disease control Sponsor: Paul Szabolcs Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 24 times

Summary

This study tests a new approach for people aged 5 to 45 with severe immune system disorders and end-stage lung disease. Participants receive a double lung transplant followed by a stem cell transplant from the same donor. The goal is to see if this combined procedure is safe and can help the body accept the new lungs without needing lifelong anti-rejection drugs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh, Pennsylvania, 15224, United States

Conditions

Explore the condition pages connected to this study.