T-B+ severe combined immunodeficiency

MONDO:0044200

T-B+ severe combined immunodeficiency (SCID) is a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes with presence of B lymphocytes, resulting in early-onset severe respiratory viral, bacterial or fungal infections, diarrhea and failure to thrive.

Also known as: T-B+ SCID, T-cell negative B-cell positive SCID

12 clinical trials for this condition and its sub-types, 0 tagged with T-B+ severe combined immunodeficiency itself.

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Where it sits in the disease tree

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↑ Severe combined immunodeficiency (37)

Sub-types of T-B+ severe combined immunodeficiency

T-B+ severe combined immunodeficiency due to gamma chain deficiency 10 trials
T-B+ severe combined immunodeficiency due to JAK3 deficiency 2 trials
T-B+ severe combined immunodeficiency due to IL-7Ralpha deficiency 1 trial
T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta 0 trials
3 sub-types
- Immunodeficiency 18 0 trials
- Immunodeficiency 19 0 trials
- Immunodeficiency 25 0 trials
T-B+ severe combined immunodeficiency due to CD45 deficiency 0 trials
Combined immunodeficiency, X-linked 0 trials
Immunodeficiency 104 0 trials
Lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome 0 trials
Severe combined immunodeficiency due to CORO1A deficiency 0 trials
Severe combined immunodeficiency due to LAT deficiency 0 trials

Including sub-types (12) Tagged with T-B+ severe combined immunodeficiency (0)

Trials to join now! 3 Not yet recruiting 1 Not yet finished but already full! 4 Completed 3 Terminated 1

T-B+ severe combined immunodeficiency

Where it sits in the disease tree

Bubble baby breakthrough? experimental cell shot aims to reboot immune system faster

Gene therapy offers hope for 'Bubble Boy' disease, but leukemia risk remains

Gene therapy offers hope for boys with severe immune disorder