Supratentorial cancer
MONDO:0002071Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and brain STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.
Also known as: malignant supratentorial neoplasm, malignant supratentorial tumor, malignant supratentorial tumour, supratentorial neoplasms, malignant
2889 clinical trials for this condition and its sub-types, 15 tagged with Supratentorial cancer itself.
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Sub-types of Supratentorial cancer
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Diencephalic cancer 0 trials · 25 incl. sub-types
3 sub-types
- Thalamic cancer 1 trial · 24 incl. sub-types Sub-types →
- Chordoid glioma of the third ventricle 1 trial
- Diencephalic astrocytomas 0 trials · 1 incl. sub-types Sub-types →
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Cerebral hemisphere cancer 0 trials · 9 incl. sub-types
10 sub-types
- Cerebral neuroblastoma 4 trials Sub-types →
- Cerebral lymphoma 2 trials
- Cerebral meningioma 0 trials · 1 incl. sub-types Sub-types →
- Cerebral primitive neuroectodermal tumor 1 trial
- Parietal lobe cancer 1 trial Sub-types →
- Childhood cerebral astrocytoma 0 trials Sub-types →
- Corpus callosum oligodendroglioma 0 trials
- Frontal lobe ependymal tumor 0 trials
- Pediatric cerebral ependymoblastoma 0 trials Sub-types →
- Temporal lobe cancer 0 trials
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Supratentorial primitive neuroectodermal tumor 5 trials · 6 incl. sub-types
1 sub-type
Most studied deeper sub-types
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Brain tumor patients may avoid Post-Surgery seizures with simple drug
Prevention Recruiting nowThis study tests whether levetiracetam, a seizure medication, can prevent seizures in adults after brain tumor surgery. About 558 participants will receive either the drug or a placebo starting one hour before surgery and continuing for three months. The goal is to see if the dru…
Phase 3 • Sponsor: Beijing Tiantan Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:39 UTC
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Which additive works best for pain control in brain surgery?
Symptom relief Recruiting nowThis trial tests whether adding ketamine or dexmedetomidine to a standard numbing drug (bupivacaine) in a scalp block improves pain control and reduces opioid use during brain tumor removal. About 80 adults undergoing supratentorial brain tumor surgery will receive one of the two…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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Less propofol during brain surgery may lead to quicker, safer awakening
Symptom relief Recruiting nowThis study is testing whether using lower doses of the anesthetic drug propofol during brain tumor surgery helps patients wake up more quickly and fully after the operation. Researchers will enroll 100 adults having elective brain surgery and monitor their recovery. The goal is t…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Stitch showdown: which scalp closure heals best after brain tumor surgery?
Knowledge-focused Recruiting nowThis study compares two common methods of closing the skin after brain tumor surgery: a continuous stitch under the skin using absorbable thread versus separate stitches through the skin using non-absorbable thread. Researchers want to see which method leads to fewer wound proble…
Sponsor: Medical University of Warsaw • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Which drug keeps the brain safer during surgery? new study aims to find out
Knowledge-focused Recruiting nowThis study tests two common blood-pressure-raising drugs, noradrenaline and phenylephrine, in 32 people undergoing brain tumor surgery. The goal is to see which drug better maintains blood flow and oxygen delivery to the brain and other organs. Researchers will use PET scans to m…
Phase 2/3 • Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Brain surgery drug interaction under the microscope
Knowledge-focused Recruiting nowThis study looks at how the drug mannitol changes levels of the anesthetic propofol in the blood and urine during brain surgery. Forty adults having either supratentorial tumor surgery or pituitary surgery will be enrolled. Half will receive mannitol, the other half a placebo, an…
Phase 4 • Sponsor: Cukurova University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:41 UTC