SUNCT syndrome

MONDO:0018927

SUNCT syndrome (Short-lasting Unilateral Neuralgiform headache attacks with Conjunctival injection and Tearing) is a primary headache disorder characterized by unilateral trigeminal pain that occurs in association with ipsilateral cranial autonomic symptoms (conjunctival injection and tearing).

Also known as: SUNCT headache, short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing, short-lasting, unilateral, neuralgiform headache attacks with conjunctival injection and tearing

12 clinical trials for this condition and its sub-types, 4 tagged with SUNCT syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Syndromic disease (7133) ↑ Trigeminal autonomic cephalalgia (27)

Including sub-types (12) Tagged with SUNCT syndrome (4)

Trials to join now! 4 Not yet recruiting 2 Not yet finished but already full! 1 Completed 5

Scientists use chili peppers and ice water to unlock headache secrets

Knowledge-focused By invitation only

This study looks at how headaches work by using capsaicin (the spicy part of chili peppers) and ice water to trigger mild, temporary pain in people with and without headache disorders. Researchers measure changes in pain signals and tear production to better understand conditions…

Phase 1 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused

Last updated Jun 27, 2026 09:05 UTC

SUNCT syndrome

Where it sits in the disease tree

Scientists use chili peppers and ice water to unlock headache secrets