Substance withdrawal syndrome
MONDO:0005567A substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of a substance (including alcohol, prescribed medications and recreational drugs). Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions.
Also known as: drug withdrawal, drug withdrawal syndrome, substance withdrawal, substance withdrawal disorder, substance withdrawal syndrome, withdrawal syndrome, withdrawal disorder
157 clinical trials for this condition and its sub-types, 30 tagged with Substance withdrawal syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Substance withdrawal syndrome
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Neonatal abstinence syndrome 18 trials
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Alcohol withdrawal 11 trials · 13 incl. sub-types
1 sub-type
- Alcohol withdrawal delirium 2 trials
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Baclofen withdrawal syndrome 0 trials
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New drug may help preemies breathe easier, avoid opioids
Symptom relief Not yet recruitingThis study tests dexmedetomidine, a sedative that doesn't slow breathing, in 246 premature babies on ventilators. The goal is to see if it reduces the need for opioids, shortens time on the breathing machine, and improves long-term brain development. Babies will receive the drug …
Phase 2/3 • Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Symptom relief
Last updated Aug 28, 2026 00:00 UTC
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Could CBD ease alcohol withdrawal? new trial aims to find out
Symptom relief Not yet recruitingThis study tests whether cannabidiol (CBD), a compound from cannabis, can reduce alcohol withdrawal symptoms and cravings in people with moderate-to-severe alcohol use disorder. 105 adults will stay in a hospital for 5 days, receive either CBD or a placebo alongside standard care…
Phase 2/3 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Aug 20, 2026 00:00 UTC