Streptococcal sore throat

This trial investigates whether a rapid C-reactive protein (CRP) blood test can help doctors decide when antibiotics are truly needed for adults with acute respiratory infections in Indonesian primary health clinics. Many such infections are viral and do not require antibiotics, …

This study tests whether ColdZyme mouth spray can lower the amount of virus people breathe out when they have a cold or flu. Researchers will measure virus particles in exhaled air before and after using the spray. The goal is to see if the spray might help reduce airborne transm…

This study tests whether giving oral antibiotics instead of IV antibiotics is just as safe and effective for patients with common infections like pneumonia, urinary tract infections, and cellulitis. About 4,000 adults in Danish emergency rooms will be randomly assigned to start o…

This study is testing a finger-prick blood test called FebriDx in 800 children aged 2-11 who have a fever and symptoms of a respiratory infection. The goal is to see if the test can quickly tell whether the infection is caused by bacteria or something else (like a virus). If accu…

This study tests a new device that uses artificial intelligence to help diagnose ear infections, strep throat, and asthma flare-ups in children. About 84 kids aged 3 to 17 will either use the device at home with a doctor's video visit or receive standard in-person care. The goal …

This study is testing a new diagnostic tool that helps doctors quickly tell if a respiratory infection is caused by bacteria or a virus. The goal is to see if using this test leads to better treatment decisions, fewer unnecessary antibiotics, and lower healthcare costs. About 100…

This study gathers fluid and tissue from the lungs and nose of healthy volunteers and people with a history of lung infections. Researchers will compare samples to find differences in immune function that might explain why some people are more prone to infections. Participants un…

This study will follow 2,000 people of all ages who visit their doctor with symptoms of an acute respiratory infection, like cough, sore throat, or runny nose. Researchers will collect information on symptoms, treatments, and lab results to better understand how these infections …

This study aims to identify the types of fungi causing pneumonia in immunocompromised ICU patients and test how resistant they are to antifungal drugs. Researchers will collect samples from 250 adults in intensive care who have pneumonia that does not respond to antibiotics. The …

This study tracks respiratory infections in thousands of patients across China to build a better early warning system. Researchers collect routine medical data and samples to identify which germs are circulating and how the body responds. The goal is to help hospitals and health …

This study tests whether implementing new Swiss national guidelines for acute respiratory infections can reduce unnecessary antibiotic prescribing in primary care. Researchers will work with 200 family doctors in quality circles and walk-in clinics, providing training and materia…

This study is observing 2,000 children under 2 years old in Ho Chi Minh City who have respiratory infections. Researchers will test for RSV, track how the virus spreads across seasons, and measure the illness's impact on families, including medical costs. No new treatments or vac…

This study tests two ways to help general practitioners (GPs) use antimicrobial stewardship resources when treating respiratory tract infections. One group gets online training and self-audit tools; the other gets face-to-face support. Researchers will track how often GPs use the…

This study looks at whether a quick lab test (Spotfire R/ST) can help doctors decide when antibiotics are truly needed for people with respiratory infections like colds or sore throats. About 800 urgent care patients will take part, and researchers will compare antibiotic use bef…

This study looks at children ages 5 to 15 who test positive for strep throat to understand why some become carriers—meaning they have the bacteria but no symptoms. Researchers will collect throat samples and analyze gene activity to compare carriers with those who have active inf…

This study will follow 1,000 adults who come to fever clinics with a respiratory infection. Researchers will collect data on symptoms, lab tests, and chest scans at the start, then check in over time to see who develops pneumonia or other complications. The goal is to better unde…

This study in Kyrgyzstan is testing whether using a rapid C-reactive protein (CRP) blood test and giving patients an information leaflet can help doctors prescribe fewer antibiotics for respiratory infections like coughs and sore throats. About 1050 adults will be randomly assign…