Soft tissue neoplasm
MONDO:0006424A benign, intermediate, or malignant neoplasm that arises from the soft tissue. The most common types are lipomatous (fatty), vascular, smooth muscle, fibrous, and fibrohistiocytic neoplasms.
Also known as: neoplasm of soft tissue, neoplasm of the soft tissue, soft tissue neoplasm, soft tissue tumor, soft tissue tumors, soft tissue tumour, soft tissue tumours, tumor of soft tissue
2133 clinical trials for this condition and its sub-types, 23 tagged with Soft tissue neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Soft tissue neoplasm
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Malignant soft tissue neoplasm 7 trials · 651 incl. sub-types
3 sub-types
- Soft tissue sarcoma 297 trials · 646 incl. sub-types Sub-types →
- Malignant central nervous system mesenchymal, non-meningothelial neoplasm 0 trials Sub-types →
- Mediastinal soft tissue cancer 0 trials Sub-types →
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Desmoid tumor 36 trials
1 sub-type
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Neoplasm with perivascular epithelioid cell differentiation 8 trials · 25 incl. sub-types
6 sub-types
- Lymphangioleiomyomatosis 11 trials Sub-types →
- Angiomyolipoma 4 trials · 5 incl. sub-types Sub-types →
- Benign PEComa 0 trials · 5 incl. sub-types Sub-types →
- Lung PEComa 0 trials · 1 incl. sub-types Sub-types →
- Uterine corpus perivascular epithelioid cell tumor 1 trial
- Lymphangiomyoma 0 trials
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Synovium neoplasm 0 trials · 17 incl. sub-types
3 sub-types
- Tenosynovial giant cell tumor 12 trials · 16 incl. sub-types Sub-types →
- Benign synovial neoplasm 0 trials · 9 incl. sub-types Sub-types →
- Synovium cancer 1 trial · 2 incl. sub-types Sub-types →
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Benign soft tissue neoplasm 0 trials · 16 incl. sub-types
10 sub-types
- Benign synovial neoplasm 0 trials · 9 incl. sub-types Sub-types →
- Benign PEComa 0 trials · 5 incl. sub-types Sub-types →
- Infantile myofibromatosis 1 trial Sub-types →
- Myxoma 1 trial
- Angiomyxoma 0 trials
- Endobronchial lipoma 0 trials
- Endometrial stromal nodule 0 trials
- Fibroosseous pseudotumor of the digits 0 trials
- Lipoblastoma 0 trials
- Soft tissue chondroma 0 trials Sub-types →
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Mixed endometrial stromal and smooth muscle tumor 0 trials · 9 incl. sub-types
4 sub-types
- Leiomyosarcoma of the corpus uteri 9 trials Sub-types →
- Uterine corpus perivascular epithelioid cell tumor 1 trial
- Endometrial stromal nodule 0 trials
- Uterine corpus rhabdomyosarcoma 0 trials
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Inflammatory myofibroblastic tumor 8 trials
5 sub-types
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Kaposiform hemangioendothelioma 4 trials
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Glomus tumor 1 trial · 3 incl. sub-types
4 sub-types
- Malignant glomus tumor 1 trial
- Skin glomus tumor 1 trial Sub-types →
- Glomangioma 0 trials Sub-types →
- Glomangiomyoma 0 trials Sub-types →
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Fibromyxoid tumor 1 trial · 2 incl. sub-types
2 sub-types
- Ossifying fibromyxoid tumor 1 trial
- Non-ossifying fibromyxoid tumor 0 trials
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Mazabraud syndrome 1 trial
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Soft tissue amyloid neoplasm 1 trial
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1 sub-type
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Congenital epulis 0 trials
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Juvenile hyaline fibromatosis 0 trials
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Mediastinal mesenchymal tumor 0 trials
1 sub-type
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Melanoma of soft tissue 0 trials
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Nodular fasciitis 0 trials
2 sub-types
- Cranial nodular fasciitis 0 trials
- Intravascular fasciitis 0 trials
Most studied deeper sub-types
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Narrow beams, big hope: new radiation approach tested for skin tumors
Disease control Recruiting nowThis study tests a new radiation method called minibeam therapy for people with skin or soft tissue tumors that have come back or spread. The treatment uses a special device to split a wide radiation beam into many tiny beams, which may reduce damage to healthy tissue. The goal i…
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Alpha radiation seeds target tumors from the inside
Disease control Recruiting nowThis study tests a device called DaRT that delivers a unique type of radiation (alpha particles) directly into tumors. It is designed for people with certain skin cancers, mouth cancers, or soft tissue sarcomas that are accessible for direct injection. The goal is to see if this …
Sponsor: Alpha Tau Medical LTD. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a blood clot replace gum surgery for dental implants?
Disease control Recruiting nowThis study compares two methods to improve gum thickness around dental implants in the front of the mouth. One method uses a platelet-rich fibrin (PRF) membrane made from the patient's own blood, while the other uses a standard connective tissue graft. The trial will enroll 26 ad…
Sponsor: Gulf Medical University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Sound waves vs. tumors: new registry tracks Non-Surgical breakthrough
Disease control Recruiting nowThis study is a registry that will follow 200 adults with soft tissue tumors who receive histotripsy, a treatment that uses focused ultrasound to break down tumors without surgery. Researchers will track how well the tumors respond and any side effects. The goal is to confirm tha…
Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New injection targets Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage study tests a new drug called tolododekin alfa (ANK-101) for people with advanced solid tumors that have not responded to standard treatments. The drug is injected directly into the tumor to see if it is safe and tolerable. About 97 adults with various solid canc…
Phase 1 • Sponsor: Ankyra Therapeutics, Inc • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Radioactive seeds zaps tumors from the inside
Disease control Recruiting nowThis study is testing a device called DaRT that delivers alpha radiation directly into tumors. It is for people with certain skin cancers, mouth cancers, or soft tissue sarcomas that are up to 7 centimeters in size. The goal is to see if the tumors shrink and to check for side ef…
Sponsor: Alpha Tau Medical LTD. • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New study aims to find best scan for Kids' tumors
Diagnosis Recruiting nowThis study compares whole-body MRI, PET/MR, and PET/CT scans to see which is best at finding tumors in children and young adults with solid tumors, lymphoma, or osteosarcoma. Researchers will check how many tumors each scan detects and measure their metabolic activity. The goal i…
Sponsor: Stanford University • Aim: Diagnosis
Last updated Jun 27, 2026 09:03 UTC
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Oxygen boost for dental implants: tiny trial tests faster healing
Symptom relief Recruiting nowThis study tests whether applying oxygen directly to the gums around dental implants can help them heal better and look nicer. Six adults who need a second-stage implant procedure will receive topical oxygen therapy alongside custom healing collars. Researchers will measure chang…
Phase 4 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Tracking the emotional toll of a cancer diagnosis: when does anxiety peak?
Knowledge-focused Recruiting nowThis study follows adults with a suspected bone or soft tissue tumor to see how their stress and anxiety levels change at three critical moments: before biopsy, after learning the diagnosis, and when treatment begins. Participants fill out standard questionnaires about anxiety, d…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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New registry tracks PEF ablation in 1,000 patients
Knowledge-focused Recruiting nowThis observational registry will follow 1,000 people who receive pulsed electric field (PEF) ablation for soft tissue lesions. The goal is to see how doctors use the device in everyday practice and to monitor safety. Participants will be treated per standard care and followed for…
Sponsor: Galvanize Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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New registry aims to unlock secrets of rare bone and soft tissue tumors
Knowledge-focused Recruiting nowThis study is creating a detailed health record database for 1500 people diagnosed with bone or soft tissue tumors. The goal is to collect high-quality information that researchers can use to better understand these rare diseases. No new treatments or medications are being tested…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC