Skin basal cell carcinoma
MONDO:0005341The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas.
Also known as: BCC, basal cell cancer, basal cell carcinoma, basal cell tumor, basal cell tumour, basal cell tumour (morphologic abnormality), malignant basal cell tumour, malignant basal cell tumour (morphologic abnormality)
2820 clinical trials for this condition and its sub-types, 51 tagged with Skin basal cell carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Skin basal cell carcinoma
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Nodular basal cell carcinoma 8 trials
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Basosquamous carcinoma 1 trial
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Morpheaform basal cell carcinoma 1 trial
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Adamantinoid basal cell epithelioma 0 trials
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Anal margin basal cell carcinoma 0 trials
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External ear basal cell carcinoma 0 trials
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Follicular basal cell carcinoma 0 trials
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Metatypical basal cell carcinoma 0 trials
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Micronodular basal cell carcinoma 0 trials
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Penis basal cell carcinoma 0 trials
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Sarcomatoid basal cell carcinoma 0 trials
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Scrotum basal cell carcinoma 0 trials
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Sebaceous basal cell carcinoma 0 trials
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Signet ring basal cell carcinoma 0 trials
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Skin adenoid basal cell carcinoma 0 trials
1 sub-type
- Cervical adenoid basal carcinoma 0 trials
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Skin clear cell basal cell carcinoma 0 trials
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Skin cystic basal cell carcinoma 0 trials
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Skin pigmented basal cell carcinoma 0 trials
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Vulva basal cell carcinoma 0 trials
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Can pairing immunotherapy drugs shrink Hard-to-Treat skin cancers?
Disease control Not yet recruitingResearchers are testing the drug cemiplimab, given alone or with other anti-cancer drugs, in people with locally advanced basal cell carcinoma that cannot be treated with surgery or radiation. The trial compares how well the combinations work against cemiplimab by itself and trac…
Phase 2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Sound waves vs. freezing: new skin cancer treatment tested
Disease control Not yet recruitingThis study tests whether high intensity focused ultrasound (HIFU) works as well as standard cryotherapy (freezing) for treating low-risk basal cell carcinomas and Bowen's disease. About 294 adults with small skin cancers on their body (not face or hands) will be randomly assigned…
Sponsor: Jussi Salonen • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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AI eye could slash skin cancer surgery time
Diagnosis Not yet recruitingThis study tests whether an AI-powered imaging tool can accurately detect the edges of common skin cancers before surgery. Researchers will compare AI-OCT scans with standard surgical results in 30 adults with basal cell carcinoma. If the AI works well, it could help surgeons rem…
Sponsor: Henry Ford Health System • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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New camera could spare skin cancer patients from unnecessary biopsies
Knowledge-focused Not yet recruitingThis study tests a non-invasive imaging technique called LC-OCT for diagnosing basal cell carcinoma, the most common skin cancer. Researchers will review medical records of about 300 patients to see if LC-OCT can accurately detect cancer and guide treatment without needing a biop…
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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New ultrasound technique aims to improve skin cancer surgery outcomes
Knowledge-focused Not yet recruitingThis study looks at whether using a high-frequency ultrasound before surgery for common skin cancers on the head and neck can help surgeons remove the entire tumor the first time. About 400 adults with basal or squamous cell skin cancer will be in the study. Some will get the sta…
Sponsor: Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC