Sickle cell-hemoglobin c disease syndrome
MONDO:0016669A rare, genetic hemoglobinopathy characterized by anemia, reticulocytosis and erythrocyte abnormalities including target cells, irreversibly sickled cells and crystal-containing cells. Clinical course is similar to sickle cell disease, but less severe and with less complications. Signs and symptoms may include acute episodes of pain, splenic infarction and splenic sequestration crisis, acute chest syndrome, focal segmental glomerulosclerosis, ischemic brain injury, peripheral retinopathy, and osteonecrosis.
Also known as: HbSC disease, sickle cell - haemoglobin C disease, sickle cell - hemoglobin C disease
21 clinical trials for this condition and its sub-types, 7 tagged with Sickle cell-hemoglobin c disease syndrome itself.
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A Pocket-Sized coach for sickle cell: can an app turn Pill-Taking into a habit?
Disease control CompletedThis study follows adolescents and young adults (ages 12–21) with sickle cell disease who take hydroxyurea, a medication that helps prevent pain crises and other complications. The researchers are testing whether a mobile app called HU-Go can help these patients build a consisten…
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Can a phone app keep teens on track with sickle cell treatment?
Disease control CompletedThis pilot trial tests whether a smartphone app called MED-Go can help adolescents and young adults with sickle cell disease take their daily hydroxyurea more consistently. Participants aged 12 to 21 will use the app for 12 weeks, and researchers will measure how often they log t…
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Can a computer program tame sickle cell pain crises?
Symptom relief CompletedThis trial tests a computer-based tool called PAINRelieveIt for adults with sickle cell disease, a condition that causes intense pain episodes. The tool has three parts: one helps patients report their pain, another educates them about pain management, and a third helps doctors c…
Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Sickle cell study reveals hidden clues in blood vessels
Knowledge-focused CompletedThis study measured blood vessel function in 49 adults with sickle cell disease to see how it relates to disease severity. Researchers used laser and pulse wave tests to check small and large blood vessels. The goal was to better understand the disease, not to test a new treatmen…
Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC