Rheumatic fever
MONDO:0017767A post-bacterial multisystem inflammatory disease occurring as a post-infectious, nonsuppurative sequela of untreated streptococcus pyogenes (Group A streptococcus [GAS]) pharyngitis, and mainly occurs in individuals aged 5 to 15 years. The most common presenting signs are fever, migratory polyarthritis and carditis.
Also known as: ARF, acute rheumatic fever, inflammatory rheumatism
51 clinical trials for this condition and its sub-types, 16 tagged with Rheumatic fever itself.
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School nurses take on heart disease: 6,000 kids in prevention trial
Prevention Recruiting nowThis trial tests whether placing trained nurses in schools can prevent rheumatic heart disease in children aged 5 to 16 in Nepal and Zambia. The nurses will teach about the disease, check for strep throat, and help kids get antibiotics. The study will measure if this approach low…
Sponsor: Thomas Pilgrim • Aim: Prevention
Last updated Jun 27, 2026 08:13 UTC
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New support program aims to help caregivers of frail seniors with arthritis
Symptom relief Recruiting nowThis study tests a new program called INSPIRE, designed to support informal caregivers (like family or friends) of older adults with rheumatoid arthritis and frailty. The program involves three sessions with a healthcare professional over 12 weeks, focusing on emotional support, …
Sponsor: Glostrup University Hospital, Copenhagen • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Can glucocorticoid treatment skew bone health tests? a study investigates
Knowledge-focused Recruiting nowThis study follows 160 people with inflammatory joint disease who are starting treatment with or without glucocorticoids, or receiving a glucocorticoid injection. Researchers will measure bone turnover markers (P1NP and CTX1) in blood samples every 4 weeks and up to 6 months afte…
Sponsor: Diakonhjemmet Hospital • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Can a simple blood or joint fluid test predict knee arthritis outcomes?
Knowledge-focused Recruiting nowThis study will follow 300 people with knee osteoarthritis or chronic inflammatory arthritis for up to 10 years. Researchers will collect blood, joint fluid, and platelet-rich plasma samples to look for biomarkers linked to pain, joint damage, and the need for knee replacement. T…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Massive study aims to unlock secrets of brain inflammation diseases
Knowledge-focused Recruiting nowThis research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…
Sponsor: Brain Inflammation Collaborative • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New study aims to catch lung disease early in arthritis patients
Knowledge-focused Recruiting nowThis study will observe 800 adults with rheumatoid arthritis in Austria to create a standard screening method for lung complications. Researchers will use CT scans, lung function tests, and AI analysis to identify those at high risk. The goal is to detect lung problems earlier an…
Sponsor: Medical University Innsbruck • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC