Rheumatic disorder
MONDO:0005554Inflammatory and degenerative diseases of connective tissue structures, such as arthritis.
Also known as: rheumatic disease, rheumatologic disorder, collagen disease, collagen vascular disease, connective tissue disease, disease, rheumatic, diseases, rheumatic, enthesopathies
1792 clinical trials for this condition and its sub-types, 90 tagged with Rheumatic disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Rheumatic disorder
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Rheumatoid arthritis 576 trials · 795 incl. sub-types
7 sub-types
- Psoriatic arthritis 188 trials · 201 incl. sub-types Sub-types →
- Ankylosing spondylitis 109 trials · 113 incl. sub-types Sub-types →
- Rheumatoid arthritis-associated interstitial lung disease 12 trials
- Chronic childhood arthritis 5 trials
- Felty syndrome 0 trials
- Polyarticular juvenile rheumatoid arthritis 0 trials
- Rheumatoid vasculitis 0 trials
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Lupus erythematosus 39 trials · 548 incl. sub-types
3 sub-types
- Systemic lupus erythematosus 516 trials · 522 incl. sub-types Sub-types →
- Cutaneous lupus erythematosus 38 trials · 46 incl. sub-types Sub-types →
- Drug-induced lupus erythematosus 1 trial
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Scleroderma 47 trials · 305 incl. sub-types
3 sub-types
- Systemic sclerosis 261 trials · 295 incl. sub-types Sub-types →
- Localized scleroderma 14 trials · 15 incl. sub-types Sub-types →
- Neonatal scleroderma 0 trials
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Autoinflammatory syndrome 21 trials · 207 incl. sub-types
37 sub-types
- Sarcoidosis 61 trials · 84 incl. sub-types Sub-types →
- Periodic fever syndrome 2 trials · 25 incl. sub-types Sub-types →
- Systemic-onset juvenile idiopathic arthritis 25 trials
- Type 1 interferonopathy 4 trials · 21 incl. sub-types Sub-types →
- Autoinflammatory syndrome of childhood 0 trials · 19 incl. sub-types Sub-types →
- VEXAS syndrome 18 trials
- Adult-onset Still disease 12 trials
- Pyoderma gangrenosum 10 trials Sub-types →
- Idiopathic recurrent pericarditis 8 trials
- PFAPA syndrome 6 trials
- Chronic recurrent multifocal osteomyelitis 3 trials · 4 incl. sub-types Sub-types →
- SAPHO syndrome 3 trials
- Schnitzler syndrome 1 trial
- Cherubism 1 trial Sub-types →
- CEBPE-associated autoinflammation-immunodeficiency-neutrophil dysfunction syndrome 0 trials
- F12-associated cold autoinflammatory syndrome 0 trials
- PAPASH syndrome 0 trials
- Pelger-Huet-like anomaly and episodic fever with abdominal pain 0 trials
- SAMD9L-associated autoinflammatory syndrome 0 trials
- Sharpin-related autoinflammatory syndrome 0 trials
- Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation 0 trials
- Autoinflammatory disease, X-linked 0 trials
- Autoinflammatory disease, multisystem, with immune dysregulation, X-linked 0 trials Sub-types →
- Autoinflammatory disease, systemic, with vasculitis 0 trials
- Autoinflammatory syndrome with immunodeficiency 0 trials
- Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis 0 trials
- Autoinflammatory syndrome, familial, Behcet-like 0 trials Sub-types →
- Autoinflammatory syndrome due to TBK1 deficiency 0 trials
- Early-onset pulmonary and cutaneous vasculitis 0 trials
- Granulomatous autoinflammatory syndrome of childhood 0 trials
- Infantile onset panniculitis with uveitis and systemic granulomatosis 0 trials
- Magic syndrome 0 trials
- Neonatal inflammatory skin and bowel disease 0 trials Sub-types →
- Neonatal-onset severe multisystemic autoinflammatory disease with increased IL18 0 trials
- Psoriasis 14, pustular 0 trials
- Pyoderma gangrenosum-acne-suppurative hidradenitis syndrome 0 trials
- Pyogenic arthritis-pyoderma gangrenosum-acne syndrome 0 trials
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Juvenile idiopathic arthritis 107 trials · 115 incl. sub-types
6 sub-types
- Systemic-onset juvenile idiopathic arthritis 25 trials
- Polyarticular juvenile idiopathic arthritis 14 trials · 16 incl. sub-types Sub-types →
- Psoriasis-related juvenile idiopathic arthritis 15 trials
- Enthesitis-related juvenile idiopathic arthritis 7 trials
- Oligoarticular juvenile idiopathic arthritis 5 trials Sub-types →
- Unspecified juvenile idiopathic arthritis 0 trials
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Dermatomyositis 81 trials · 100 incl. sub-types
11 sub-types
- Juvenile dermatomyositis 41 trials
- Anti-MDA5 dermatomyositis 3 trials
- Clinically amyopathic dermatomyositis 1 trial · 2 incl. sub-types Sub-types →
- Adermatopathic dermatomyositis 0 trials
- Adult dermatomyositis 0 trials
- Anti-Mi2 dermatomyositis 0 trials
- Anti-NXP2 dermatomyositis 0 trials
- Anti-SAE dermatomyositis 0 trials
- Anti-TIF1 dermatomyositis 0 trials
- Classical dermatomyositis 0 trials
- Neonatal dermatomyositis 0 trials
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Polymyalgia rheumatica 30 trials
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Rheumatic fever 16 trials
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Mixed connective tissue disease 15 trials
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Reactive arthritis 6 trials
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Gorham-Stout disease 2 trials
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Sweet syndrome 2 trials
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Palindromic rheumatism 1 trial
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2 sub-types
- Inflammatory bowel disease 25 0 trials
- Inflammatory bowel disease 28 0 trials
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LAMA5-related multisystemic syndrome 0 trials
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Reye syndrome 0 trials
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Wissler syndrome 0 trials
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Acroosteolysis dominant type 0 trials
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Chondrocalcinosis 2 0 trials
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Fibroblastic rheumatism 0 trials
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Idiopathic juvenile osteoporosis 0 trials
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Intermittent hydrarthrosis 0 trials
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Progeria-associated arthropathy 0 trials
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Rheumatic pulmonary valve disease 0 trials
Most studied deeper sub-types
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Yearly TB check may shield vulnerable patients from a hidden threat
Prevention Not yet recruitingThis trial investigates whether annual re-screening for tuberculosis infection using a blood test (IGRA) can prevent active TB in people with autoimmune rheumatic diseases who are taking biologic or immunosuppressive medications. Participants who initially test negative for TB ar…
Sponsor: University of Sao Paulo General Hospital • Aim: Prevention
Last updated Aug 20, 2026 00:00 UTC
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Could one antibiotic dose before tooth pulling prevent infections in Immune-Weakened patients?
Prevention Not yet recruitingThis study tests whether a single dose of amoxicillin before a simple tooth extraction can prevent infections in people with autoimmune rheumatic diseases who are on immune-suppressing medications. Researchers will compare infection rates between those who get the antibiotic and …
Phase 4 • Sponsor: University of Sao Paulo General Hospital • Aim: Prevention
Last updated Aug 08, 2026 00:03 UTC
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Can better sleep ease pain in teens with rheumatic disease?
Symptom relief Not yet recruitingThis study explores whether a self-guided web program called 'Better Nights, Better Days for Youth' can improve sleep and reduce pain in teenagers with rheumatic diseases like arthritis and lupus. Teens aged 12-18 with sleep problems will track their sleep and pain daily, then us…
Sponsor: The Hospital for Sick Children • Aim: Symptom relief
Last updated Aug 22, 2026 00:00 UTC
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Nursing Students' back pain targeted in new exercise study
Symptom relief Not yet recruitingThis study looks at how common neck and low back pain is among nursing students at the University of the West Indies, and tests whether a spine-specific exercise program works better than general exercises to ease that pain. About 400 students with pain will be randomly assigned …
Sponsor: The University of The West Indies • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Can sound waves boost arthritis shots?
Symptom relief Not yet recruitingThis study tests whether using ultrasound therapy before a steroid injection into the joint can improve pain and swelling for people with arthritis. About 100 adults with arthritis in their arms or legs will receive the combined treatment. The goal is to see if the ultrasound hel…
Sponsor: Taichung Veterans General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New study tests brain training and nerve zaps to ease arthritis pain
Symptom relief Not yet recruitingThis study will test two non-drug approaches—pain neuroscience education and vagus nerve stimulation—against traditional exercise in 36 people with rheumatoid arthritis. The goal is to see which method best reduces pain, improves quality of life, and lowers inflammation over 8 we…
Sponsor: Medipol University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Can a Self-Image workshop help rheumatic disease patients feel better about themselves?
Symptom relief Not yet recruitingThis study tests a therapeutic education program designed to improve self-image and self-esteem in adults with chronic inflammatory rheumatic diseases like rheumatoid arthritis and spondyloarthritis. Sixty participants will complete questionnaires and interviews before and after …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 15:59 UTC
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Can a prefilled pen match a syringe for this biosimilar?
Knowledge-focused Not yet recruitingThis study compares two ways of giving the same experimental biosimilar drug, DRL_AB, which is designed to work like abatacept for autoimmune conditions. Healthy male volunteers receive a single dose either through an autoinjector or a prefilled syringe. Researchers measure how m…
Phase 1 • Sponsor: Dr. Reddy's Laboratories Limited • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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New study aims to unravel mysteries of common inflammatory condition in older adults
Knowledge-focused Not yet recruitingThis study will follow 400 people recently diagnosed with polymyalgia rheumatica, a condition causing shoulder and hip pain. Researchers will track symptoms, treatments, and outcomes over 5 years to better understand the disease and improve diagnosis. Participants will provide bl…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Can Sauna-Like heat help chronic pain? new study investigates
Knowledge-focused Not yet recruitingThis study looks at how whole-body heat therapy (hyperthermia) changes body temperature, pain sensitivity, and pain during movement in 60 people—half with chronic widespread pain (like fibromyalgia) and half healthy. Participants will receive six heat sessions over three weeks. T…
Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New study aims to predict best treatments for rheumatoid diseases using AI and health data
Knowledge-focused Not yet recruitingThis study will collect health information, samples, and data from 100 people in Luxembourg (800 total across Europe) who have rheumatoid diseases and are starting or changing treatment. Researchers hope to find patterns that can predict which treatments work best for each person…
Sponsor: Luxembourg Institute of Health • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:31 UTC