Retinal degeneration
MONDO:0004580Degeneration of the retina.
Also known as: retina degeneration, retina, Degeneration Of
582 clinical trials for this condition and its sub-types, 41 tagged with Retinal degeneration itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Retinal degeneration
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Inherited retinal dystrophy 41 trials · 510 incl. sub-types
105 sub-types
- Age-related macular degeneration 190 trials · 334 incl. sub-types Sub-types →
- Retinitis pigmentosa 84 trials · 89 incl. sub-types Sub-types →
- Hereditary macular dystrophy 3 trials · 70 incl. sub-types Sub-types →
- Cone-rod dystrophy 17 trials · 21 incl. sub-types Sub-types →
- Leber congenital amaurosis 10 trials · 12 incl. sub-types Sub-types →
- ABCA4-related retinopathy 7 trials · 11 incl. sub-types Sub-types →
- BEST1-related dominant retinopathy 1 trial · 7 incl. sub-types Sub-types →
- RHO-related retinopathy 0 trials · 7 incl. sub-types Sub-types →
- RPE65-related recessive retinopathy 5 trials · 7 incl. sub-types Sub-types →
- RPGR-related retinopathy 0 trials · 7 incl. sub-types Sub-types →
- Choroideremia 6 trials Sub-types →
- PRPF31-related retinopathy 1 trial · 4 incl. sub-types Sub-types →
- X-linked retinoschisis 4 trials
- Ornithine aminotransferase deficiency 4 trials
- ELOVL4-related maculopathy 0 trials · 3 incl. sub-types Sub-types →
- RLBP1-related retinopathy 2 trials · 3 incl. sub-types Sub-types →
- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations 3 trials
- BEST1-related recessive retinopathy 0 trials · 2 incl. sub-types Sub-types →
- EYS-related retinopathy 1 trial · 2 incl. sub-types Sub-types →
- LCA5-related retinopathy 1 trial · 2 incl. sub-types Sub-types →
- PRPH2-related retinopathy 1 trial · 2 incl. sub-types Sub-types →
- Revesz syndrome 2 trials
- Late-onset retinal degeneration 2 trials
- AIPL1-related retinopathy 1 trial Sub-types →
- ATF6-related retinopathy 0 trials · 1 incl. sub-types Sub-types →
- CNGB1-related retinopathy 0 trials · 1 incl. sub-types Sub-types →
- FLVCR1-related retinopathy with or without ataxia 0 trials · 1 incl. sub-types Sub-types →
- GUCY2D retinopathy 0 trials · 1 incl. sub-types Sub-types →
- RDH5-related retinopathy 0 trials · 1 incl. sub-types Sub-types →
- Retinoschisis of fovea 1 trial
- ADAM9-related retinopathy 0 trials Sub-types →
- CACNA1F-related retinopathy 0 trials Sub-types →
- CACNA2D4-related retinopathy 0 trials Sub-types →
- CDHR1-related retinopathy 0 trials Sub-types →
- CERKL-related retinopathy 0 trials Sub-types →
- CNGA1-related retinopathy 0 trials Sub-types →
- CNGA3-related retinopathy 0 trials Sub-types →
- CRX-related retinopathy 0 trials Sub-types →
- GNAT2-related retinopathy 0 trials Sub-types →
- GPR179-related retinopathy 0 trials Sub-types →
- GRM6-related retinopathy 0 trials Sub-types →
- GUCA1A-related retinopathy 0 trials Sub-types →
- HGSNAT-related retinopathy 0 trials Sub-types →
- IDH3B-related retinopathy 0 trials Sub-types →
- IMPDH1-related retinopathy 0 trials Sub-types →
- IMPG1-related dominant retinopathy 0 trials Sub-types →
- IMPG1-related recessive retinopathy 0 trials Sub-types →
- IMPG2-related dominant retinopathy 0 trials Sub-types →
- IMPG2-related recessive retinopathy 0 trials Sub-types →
- KCNV2-related retinopathy 0 trials Sub-types →
- KIZ-related retinopathy 0 trials Sub-types →
- LRIT3-related retinopathy 0 trials Sub-types →
- MAK-related retinopathy 0 trials Sub-types →
- MERTK-related retinopathy 0 trials Sub-types →
- MRCS syndrome 0 trials
- NMNAT1-related retinopathy 0 trials Sub-types →
- NYX-related retinopathy 0 trials Sub-types →
- Oguchi disease 0 trials Sub-types →
- PCARE-related retinopathy 0 trials Sub-types →
- PDE6A-related retinopathy 0 trials Sub-types →
- PDE6C-related retinopathy 0 trials Sub-types →
- PDE6G-related retinopathy 0 trials Sub-types →
- PROM1-related retinopathy 0 trials Sub-types →
- PRPF8-related retinopathy 0 trials Sub-types →
- RAB28-related retinopathy 0 trials Sub-types →
- RD3-related retinopathy 0 trials Sub-types →
- RDH12-related dominant retinopathy 0 trials
- RDH12-related recessive retinopathy 0 trials Sub-types →
- REEP6-related retinopathy 0 trials Sub-types →
- RP1-related dominant retinopathy 0 trials
- RP1-related recessive retinopathy 0 trials
- RP2-related retinopathy 0 trials Sub-types →
- RPE65-related dominant retinopathy 0 trials Sub-types →
- SNRNP200-related dominant retinopathy 0 trials Sub-types →
- SPATA7-related retinopathy 0 trials Sub-types →
- Sorsby fundus dystrophy 0 trials Sub-types →
- TOPORS-related retinopathy 0 trials Sub-types →
- TRPM1-related retinopathy 0 trials Sub-types →
- TTLL5-related retinopathy 0 trials Sub-types →
- X-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome 0 trials
- X-linked retinal dysplasia 0 trials
- Aceruloplasminemia 0 trials
- Amaurosis-hypertrichosis syndrome 0 trials
- Choroideremia-deafness-obesity syndrome 0 trials
- Dystrophies primarily involving the retinal pigment epithelium 0 trials
- Ectopia lentis-chorioretinal dystrophy-myopia syndrome 0 trials
- Familial benign flecked retina 0 trials
- Foveal hypoplasia-presenile cataract syndrome 0 trials
- Helicoid peripapillary chorioretinal degeneration 0 trials
- Infantile cerebellar-retinal degeneration 0 trials
- Macular degeneration, early-onset 0 trials
- Microcephaly and chorioretinopathy 1 0 trials
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Microcornea-myopic chorioretinal atrophy 0 trials
- Oligocone trichromacy 0 trials
- Pigmented paravenous retinochoroidal atrophy 0 trials
- Progressive bifocal chorioretinal atrophy 0 trials
- Progressive retinal dystrophy due to retinol transport defect 0 trials
- Retinal degeneration-nanophthalmos-glaucoma syndrome 0 trials
- Retinal dystrophies primarily involving Bruch's membrane 0 trials Sub-types →
- Retinal dystrophy in systemic or cerebroretinal lipidoses 0 trials
- Retinal dystrophy with inner retinal dysfunction and ganglion cell anomalies 0 trials
- Retinal dystrophy, X-linked, Gardner-Hardcastle type 0 trials
- Retinoschisis, autosomal dominant 0 trials
- Vitreoretinal dystrophy 0 trials
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Macular degeneration 212 trials · 426 incl. sub-types
9 sub-types
- Degeneration of macula and posterior pole 0 trials · 354 incl. sub-types Sub-types →
- Stargardt disease 33 trials · 34 incl. sub-types Sub-types →
- Macular retinal edema 19 trials · 27 incl. sub-types Sub-types →
- Vitelliform macular dystrophy 6 trials · 10 incl. sub-types Sub-types →
- Autosomal recessive bestrophinopathy 2 trials
- Isolated macular dystrophy 0 trials
- Macular degeneration, early-onset 0 trials
- Occult macular dystrophy 0 trials
- Patterned macular dystrophy 0 trials Sub-types →
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Retinoschisis 5 trials · 6 incl. sub-types
5 sub-types
- X-linked retinoschisis 4 trials
- Retinoschisis of fovea 1 trial
- Bullous retinoschisis 0 trials
- Flat retinoschisis 0 trials
- Retinoschisis, autosomal dominant 0 trials
-
Peripheral retinal degeneration 1 trial · 2 incl. sub-types
6 sub-types
- Retinal lattice degeneration 1 trial
- Blessig's cysts 0 trials
- Cobblestone retinal degeneration 0 trials
- Pseudoretinitis pigmentosa 0 trials
- Secondary vitreoretinal degeneration 0 trials
- Senile reticular retinal degeneration 0 trials
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Cone dystrophy 1, X-linked 0 trials
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Cone dystrophy 5, X-linked 0 trials
Most studied deeper sub-types
Wet macular degeneration
(159)
Dry age related macular degeneration
(91)
Preretinal fibrosis
(21)
Macular corneal dystrophy
(13)
Bietti crystalline corneoretinal dystrophy
(9)
Cystoid macular edema
(9)
Severe early-childhood-onset retinal dystrophy
(8)
Retinitis pigmentosa 3
(7)
Vitelliform macular dystrophy 2
(7)
Retinitis pigmentosa 4
(5)
Cone dystrophy
(4)
Retinitis pigmentosa 11
(4)
Congenital stationary night blindness autosomal dominant 1
(3)
Retinitis pigmentosa 39
(3)
Stargardt disease 3
(3)
Adult-onset foveomacular vitelliform dystrophy
(2)
Blue cone monochromacy
(2)
Leber congenital amaurosis 10
(2)
Leber congenital amaurosis 2
(2)
Leber congenital amaurosis 5
(2)
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Magnetic pulses to the brain may help the blind see again
Symptom relief Not yet recruitingThis clinical trial tests whether transcranial magnetic stimulation (TMS) can restore vision in adults with severe retinal degeneration. Over 100 participants will receive either real TMS or a sham (fake) treatment for five days, and their eyesight will be checked up to a year la…
Sponsor: Shanghai High Myopia Study Group • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Scientists track eye disease patterns to speed future cures
Knowledge-focused Not yet recruitingThis study looks back at medical records of 200 people with inherited retinal diseases, like retinitis pigmentosa and Stargardt disease. Researchers will analyze vision tests and eye scans to see how these diseases progress and how genetics affect symptoms. The goal is to find be…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC