Renal osteodystrophy

This study looks at whether lowering high parathyroid hormone levels can help protect bone density in people with advanced chronic kidney disease. About 70 adults aged 50 and older with kidney failure not on dialysis will be assigned to different treatment targets for their hormo…

This study will follow 1000 adults with advanced chronic kidney disease (stage 4-5) to learn why they face higher risks of bone fractures and heart disease. Researchers will track bone turnover markers, calcium and phosphate levels, and kidney function over time. No new treatment…

This study is testing whether a blood test that looks at tiny genetic molecules called microRNAs can accurately detect bone problems in people with chronic kidney disease. Currently, doctors rely on a bone biopsy, which is invasive and not practical for most patients. The researc…

This study tests a new, non-invasive method using calcium isotope ratios in blood to see if the drug cinacalcet improves bone calcium balance in children aged 3-17 who are on dialysis and have secondary hyperparathyroidism. Researchers will measure these ratios before and three m…

This study is testing how different levels of dietary phosphorus affect people with moderate chronic kidney disease (stages 3-4) compared to healthy volunteers. Participants will follow three different phosphorus diets over 21 days, and researchers will measure blood markers to f…

This study aims to understand the link between calcium and phosphorus from food and the stage of kidney disease in patients with advanced chronic kidney disease (stage 4-5). Researchers will compare two methods of tracking diet: taking photos of meals and weighing food. The goal …