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New blood test could end painful bone biopsies for kidney disease patients

NCT ID NCT05880914

First seen Jun 12, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This study is testing whether a blood test that looks at tiny genetic molecules called microRNAs can accurately detect bone problems in people with chronic kidney disease. Currently, doctors rely on a bone biopsy, which is invasive and not practical for most patients. The researchers will compare the blood test results to actual bone tissue samples from 40 participants to see if the test works. If it does, it could make diagnosing and treating bone disease much easier.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Washington University in St. Louis (WashU)

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test that helps doctors choose the right bone treatment for kidney disease patients without needing a painful bone biopsy.

What could go wrong

This is a small, early-stage study with only 40 participants, so the results may not apply to everyone. The test might not be accurate enough to replace current methods.

Conditions

The condition(s) this trial relates to.

bone remodeling disease chronic kidney disease chronic renal failure syndrome renal osteodystrophy secondary hyperparathyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.