Refractive error

This study looks at whether giving free reading or distance glasses to older adults in rural areas can slow down memory and thinking problems. About 964 people aged 60-79 with poor eyesight but normal hearing and memory will take part. Half will get glasses, and the other half wi…

This study is testing whether providing free glasses to older adults in India who need them can slow down age-related cognitive decline. Over 800 people aged 60 and older with uncorrected vision problems will be randomly assigned to receive glasses or not. Researchers will track …

This study tests a machine learning model that predicts how much nearsightedness a person has without using dilating eye drops. The model uses standard eye measurements like autorefraction and corneal shape. If accurate, it could make eye exams quicker and more comfortable for ad…

This trial tests whether a wearable device that tracks and reminds children to spend more time outdoors can help prevent nearsightedness (myopia). Primary school students with adequate hyperopic reserve—a natural buffer against myopia—will be randomly assigned to either a program…

This trial tests whether auricular acupressure—small adhesive patches with seeds placed on specific ear points—can prevent myopia in children who are at higher risk. Primary school students in grades 1-4 with insufficient hyperopic reserve (a sign they may become nearsighted) wil…

This trial tests whether combining auricular acupressure (small seeds placed on the ear) with defocus spectacle lenses can slow the progression of nearsightedness (myopia) in primary school children. About 358 students in grades 1-4 with premyopia or myopia will be randomly assig…

This study tests two ways to prevent or slow myopia (short-sightedness) in children aged 7 to 10. One group gets special classroom lights that mimic sunlight, another group's parents get a smartphone app that encourages more outdoor time, and a third group gets standard care. Ove…

This trial tests whether a small adjustment during SMILE laser surgery—compensating for the eye's natural offset (kappa angle)—can improve visual quality for people with nearsightedness. About 224 participants will receive either standard SMILE or SMILE with this compensation. Re…

This study tests two different methods of centering laser eye surgery (SMILE) in people with nearsightedness and a large angle kappa—a natural offset between the visual axis and pupil center. One method uses a 50% correction, the other 100%. Researchers want to see which approach…

This study tests if a newer laser method (PRESBYOND laser blended vision) is better than standard monovision LASIK for treating presbyopia, which makes it hard to see up close as you age. About 100 adults aged 40 to 55 will be randomly assigned to one of the two surgeries. They w…

This study looks at how quickly and comfortably children aged 6 to 12 with nearsightedness (myopia) get used to special A.M.L. glasses. Forty children will wear the lenses for two weeks and report any discomfort. The goal is to see if most kids adapt within 4 to 6 days without pr…

This study is testing a new type of daily disposable contact lens called UNICON. It will involve 35 adults who already wear soft contact lenses. Participants will wear the test lenses for up to 13 weeks to see if they are safe and comfortable for correcting nearsightedness.

This pilot study looks at whether refractive surgeries like LASIK change the results of optical coherence tomography (OCT), a common eye scan used to monitor conditions like glaucoma. Researchers will measure the thickness of the retina and other eye layers before and after surge…

This study is developing imaging and computer simulation tools to predict how a person's cornea (the clear front part of the eye) will change after treatments like crosslinking for keratoconus or LASIK for vision correction. Researchers will take detailed images of the eyes of 60…

This observational study in 120 healthy young adults aged 21-25 examines whether facial features are linked to eye measurements like eye length, which affects nearsightedness or farsightedness. Participants undergo non-invasive eye exams and 3D facial scans. The goal is to better…

This study is testing whether a computer program called EpiMaster can accurately predict how well laser eye surgery (PTK-PRK) will correct nearsightedness. Researchers will compare the software's predictions to the actual vision results in 150 patients six months after surgery. T…

This study is testing whether three different prototype soft contact lenses can cause a short-term change in the thickness of the choroid (a layer at the back of the eye) in people with nearsightedness (myopia). Twenty volunteers aged 18 to 25 will wear each lens for one hour, an…