LASIK may skew eye scans: new study investigates
NCT ID NCT05856786
First seen Jun 27, 2026 · Last updated Aug 27, 2026 · Updated 2 times
Summary
This pilot study looks at whether refractive surgeries like LASIK change the results of optical coherence tomography (OCT), a common eye scan used to monitor conditions like glaucoma. Researchers will measure the thickness of the retina and other eye layers before and after surgery in 33 patients. The goal is to help doctors accurately interpret OCT scans after such procedures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better interpret OCT scans after refractive surgery, improving monitoring of eye diseases.
- What could go wrong
- This is a small pilot study with only 33 participants, so results may not apply to everyone. It is designed to gather knowledge, not to test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 33 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All subjects in the study will be adults aged 19 years or more, that fits the typical age profile of patients in the refractive surgery clinic. Refractive surgery is an elective surgery and the patients are encouraged to ask questions about the study. This is an observational study and all aspects of care, including procedures, visits, and exams, carried out as part of the study represent standard of care. Patients visiting the refractive surgery clinic will be given an option to participate in the study if they meet the selection criteria. The clinical care of the patient will not be affected by the patient's participation or non-participation in the study.
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients undergoing refractive surgery 2. For patients undergoing bilateral eye surgery, the one with higher degree of ametropia will be included. Exclusion Criteria: 1. Astigmatism more than 3 Diopters 2. Visual acuity worse than 20/25 3. Patients with unstable visual fixation 4. Severe Dry Eye
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Unversity of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68105, United States
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