Pyoderma

This study will test hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — for over 30 conditions, including long COVID, Crohn's disease, frostbite, and multiple sclerosis. Researchers will track 100 patients to see if HBOT improves their quality of …

This phase 2 trial tests whether a topical cream containing ruxolitinib (OPZELURA) can completely heal painful ulcers in adults with pyoderma gangrenosum, a chronic inflammatory skin condition. About 12 participants will apply the cream twice daily for 24 weeks while continuing s…

This study tests whether bimekizumab, a drug already approved for other skin conditions, can help heal wounds in people with pyoderma gangrenosum (PG), a rare and painful skin disorder. Adults with PG will receive injections of bimekizumab every few weeks for 24 weeks. The main g…

This phase 2 study tests an injection called SHR-1139 in 20 adults with pyoderma gangrenosum, a rare condition causing painful skin ulcers. The goal is to see if the drug can completely close the ulcers and how safe it is. Researchers will also measure how the body processes the …

Researchers are studying where the bacteria that infect skin sores come from in people with scabies or atopic dermatitis. They will compare bacteria grown from infected skin lesions with bacteria from nasal swabs to see if the same species appear in both places. A group of health…

This observational study looks at whether children aged 3 months to 16 years are more likely to complete their full course of antibiotics when prescribed at a primary care clinic versus a hospital emergency department. Researchers surveyed parents by phone after treatment ended t…

This study looks at how certain immune cells, called MAIT cells, behave in people with hidradenitis suppurativa (HS), a painful skin condition. Researchers will take skin and blood samples from 45 adults with HS and compare them to samples from people with other skin diseases. Th…