Pure red-cell aplasia
MONDO:0001705A disease characterized by normocytic, normochromic anemia, low hematocrit, reticulocytopenia, and selective erythroid hypoplasia.
Also known as: PRCA, Pure Red Cell Aplasia, Acquired, pure red cell aplasia
33 clinical trials for this condition and its sub-types, 5 tagged with Pure red-cell aplasia itself.
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Sub-types of Pure red-cell aplasia
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Diamond-Blackfan anemia 17 trials
22 sub-types
- Diamond-Blackfan anemia 1 1 trial
- Diamond-Blackfan anemia 10 0 trials
- Diamond-Blackfan anemia 11 0 trials
- Diamond-Blackfan anemia 12 0 trials
- Diamond-Blackfan anemia 13 0 trials
- Diamond-Blackfan anemia 14 with mandibulofacial dysostosis 0 trials
- Diamond-Blackfan anemia 15 with mandibulofacial dysostosis 0 trials
- Diamond-Blackfan anemia 16 0 trials
- Diamond-Blackfan anemia 17 0 trials
- Diamond-Blackfan anemia 18 0 trials
- Diamond-Blackfan anemia 19 0 trials
- Diamond-Blackfan anemia 2 0 trials
- Diamond-Blackfan anemia 20 0 trials
- Diamond-Blackfan anemia 21 0 trials
- Diamond-Blackfan anemia 22 0 trials
- Diamond-Blackfan anemia 3 0 trials
- Diamond-Blackfan anemia 4 0 trials
- Diamond-Blackfan anemia 5 0 trials
- Diamond-Blackfan anemia 6 0 trials
- Diamond-Blackfan anemia 7 0 trials
- Diamond-Blackfan anemia 8 0 trials
- Diamond-Blackfan anemia 9 0 trials
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Adult pure red cell aplasia 2 trials
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Cheap drug combo may tame tough anemia
Disease control CancelledThis trial tests a combination of two drugs, sirolimus and all-trans retinoic acid (ATRA), for people with autoimmune anemia that has not responded to standard treatments. Autoimmune anemia occurs when the immune system attacks red blood cells, causing fatigue and other symptoms.…
Phase 4 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New drug combo aims to make bone marrow transplants safer for kids
Disease control OngoingThis pilot study tests a fludarabine-based drug regimen to prepare children with bone marrow failure syndromes for a bone marrow transplant from a matched sibling donor. The goal is to help the donor cells successfully take root while reducing serious side effects. The study incl…
Early phase 1 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Could a cancer drug fix blood cell problems after transplant?
Disease control OngoingThis phase 2 trial tests whether isatuximab can help people whose blood cell counts stay low after a stem cell transplant for blood cancer. The study enrolls 12 adults whose disease is in remission but who have developed immune-related blood cell deficiencies. Participants receiv…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New blood treatment could block zika in transfusions
Disease control OngoingThis study tests a special treatment for red blood cells that aims to kill the Zika virus, making transfusions safer. About 692 people who need blood transfusions will receive either treated or standard blood. The goal is to see if the treated blood works just as well and is safe…
Phase 3 • Sponsor: Cerus Corporation • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Scientists unravel genetic secrets of bone marrow failure
Knowledge-focused By invitation onlyThis study aims to understand the genetic and molecular changes in people with bone marrow failure disorders. Researchers will analyze blood and bone marrow samples from up to 1,400 participants to track how these changes evolve over time. The goal is to better predict disease ou…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New algorithm aims to catch ovarian damage early in young cancer survivors
Knowledge-focused CancelledThis study was designed to see if a new monitoring algorithm could detect early signs of ovarian damage in women and girls who had cancer treatment. Researchers planned to compare a group using the new algorithm with a group that received standard care. However, the study was wit…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:42 UTC