Progressive familial heart block, type 1A
MONDO:0007240An autosomal dominant inherited cardiac bundle branch disorder which can progress to complete heart block.
Also known as: Lenegre's disease, PFHB1A, SCN5A progressive familial heart block, heart block, progressive, type IA, progressive familial heart block caused by mutation in SCN5A, progressive familial heart block, type IA, Cardiac conduction defect, nonprogressive, Cardiac conduction defect, progressive
53 clinical trials for this condition and its sub-types, 19 tagged with Progressive familial heart block, type 1A itself.
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Precision lead placement could boost heart failure device success
Disease control CompletedThis study tested whether placing the left ventricle lead of a cardiac resynchronization therapy (CRT) device at the heart's latest electrical activation spot improves outcomes. It included 1,000 heart failure patients with bundle branch block. The goal was to see if this targete…
Sponsor: Aarhus University Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New heart pacing technique could offer alternative for heart failure patients
Disease control CompletedThis study compared a newer pacing method, called HIS or left bundle branch (LBB) pacing, to the standard biventricular pacing in 150 heart failure patients with a specific heart electrical problem (left bundle branch block). The goal was to see if the new method could improve he…
Sponsor: Rigshospitalet, Denmark • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Where you inject matters: study tests best spot for back pain block
Symptom relief CompletedThis completed study looked at 90 people with lower back pain from conditions like herniated discs or spinal stenosis. Researchers compared two different target areas for injecting numbing medicine during a lumbar spine block to see which provides better pain relief and blood flo…
Sponsor: Keimyung University Dongsan Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Can exercise MRI reveal hidden heart issues in pacemaker patients?
Knowledge-focused CompletedThis study looks at whether it is safe and possible to do a special exercise test (MRI combined with a bike workout) in 20 people who already have a specific type of pacemaker. The goal is to see how different pacemaker settings affect the heart's pumping ability during light exe…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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New strategy may cut unnecessary pacemakers after heart valve procedure
Knowledge-focused CompletedThis study tested a new way to predict dangerous heart rhythm problems after a common heart valve procedure called TAVR. Researchers combined ECG results with CT scan measurements and implant depth to see if they could safely identify low-risk patients. The study looked back at 2…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New mapping technique may improve pacing for heart failure patients
Knowledge-focused CompletedThis study looked at 18 heart failure patients with a specific heart block to find the best spots for pacing the heart's natural electrical system. Doctors used a 3D mapping system during device implant to see where pacing corrects the heart's rhythm. The goal was to gather infor…
Sponsor: Abbott Medical Devices • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC