Precision lead placement could boost heart failure device success
NCT ID NCT03280862
First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 37 times
Summary
This study tested whether placing the left ventricle lead of a cardiac resynchronization therapy (CRT) device at the heart's latest electrical activation spot improves outcomes. It included 1,000 heart failure patients with bundle branch block. The goal was to see if this targeted approach reduces death or unplanned heart failure hospitalizations compared to standard lead placement.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aalborg University Hospital
Aalborg, 9000, Denmark
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Aarhus University Hospital
Aarhus, 8200, Denmark
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Gentofte University Hospital
Gentofte Municipality, 2900, Denmark
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Odense University Hospital
Odense, 5000, Denmark
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Rigshospitalet
Copenhagen, 2100, Denmark
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cardiac resynchronization therapy (CRT) device implantation
What this could lead to
If successful, this approach could reduce deaths and hospitalizations for heart failure patients by improving how the device is placed.
What could go wrong
The trial is completed but results are not yet widely confirmed. Targeted placement may increase procedure time, infection risk, or radiation exposure, and might not benefit all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.