Premenstrual dysphoric disorder
MONDO:1010182A severe form of premenstrual syndrome (PMS) that involves significant emotional and physical symptoms in the week or two before a period.
Also known as: PMDD
14 clinical trials for this condition and its sub-types, 14 tagged with Premenstrual dysphoric disorder itself.
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Psilocybin microdoses put to the test for severe PMS mood symptoms
Symptom relief Not yet recruitingResearchers are testing whether a psilocybin-based drug called MLS101 is safe and tolerable for premenopausal women with premenstrual dysphoric disorder (PMDD), a condition that causes intense mood and physical symptoms before menstruation. The trial enrolls 32 women aged 18 to 5…
Phase 1 • Sponsor: MycoMedica Life Sciences PBC • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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New study tests sleep workshop as Drug-Free aid for PMDD
Symptom relief Not yet recruitingThis study tests a brief sleep-focused workshop for people with PMDD who have trouble sleeping. The workshop teaches about sleep and simple strategies to improve it. Researchers want to see if it's practical and helpful, using sleep diaries and activity watches. 72 participants w…
Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Could a tiny dose of LSD ease PMS? new study investigates
Symptom relief Not yet recruitingThis study tests whether very low doses of LSD (10 micrograms) taken daily or every other day during the premenstrual phase can reduce symptoms of severe PMS or PMDD. 150 women will be randomly assigned to LSD or placebo for three menstrual cycles. The goal is to see if LSD can s…
Sponsor: Friederike Holze • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Could a hyperactive immune system fuel PMDD? a new study investigates
Knowledge-focused Not yet recruitingThis study explores whether inflammation in the body is linked to the mood and psychological symptoms of Premenstrual Dysphoric Disorder (PMDD). Researchers will compare women with PMDD to healthy controls, tracking daily emotions and behaviors over two menstrual cycles and takin…
Sponsor: King's College London • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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New study links menstrual cycle to emotional struggles in autistic women
Knowledge-focused Not yet recruitingThis study looks at how emotional regulation varies across the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better underst…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC