Pituitary gland disorder
MONDO:0003381A disease involving the pituitary gland.
Also known as: disease of pituitary gland, disease or disorder of pituitary gland, disorder of pituitary gland, pituitary gland disease, pituitary gland disease or disorder, pituitary gland disorder
175 clinical trials for this condition and its sub-types, 18 tagged with Pituitary gland disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Pituitary gland disorder
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Pituitary tumor 23 trials · 83 incl. sub-types
9 sub-types
- Pituitary gland adenoma 34 trials · 67 incl. sub-types Sub-types →
- Functioning pituitary gland neoplasm 0 trials · 24 incl. sub-types Sub-types →
- Prolactin producing pituitary tumor 2 trials · 11 incl. sub-types Sub-types →
- Non-functioning pituitary gland neoplasm 0 trials · 9 incl. sub-types Sub-types →
- Growth hormone-producing pituitary gland neoplasm 0 trials · 5 incl. sub-types Sub-types →
- Pituitary cancer 2 trials · 4 incl. sub-types Sub-types →
- ACTH-producing pituitary gland neoplasm 1 trial Sub-types →
- Benign neoplasm of pituitary gland 0 trials
- Posterior pituitary gland neoplasm 0 trials Sub-types →
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Anterior pituitary gland disorder 1 trial · 60 incl. sub-types
2 sub-types
- Hyperpituitarism 0 trials · 59 incl. sub-types Sub-types →
- Adenohypophysitis 0 trials
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Hypopituitarism 5 trials · 46 incl. sub-types
3 sub-types
- Combined pituitary hormone deficiencies, genetic form 1 trial · 42 incl. sub-types Sub-types →
- Acquired pituitary hormone deficiency 0 trials · 1 incl. sub-types Sub-types →
- Kaplowitz-Bodurtha syndrome 0 trials
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Neurohypophyseal diabetes insipidus 9 trials
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Inappropriate ADH syndrome 5 trials
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Hypophysitis 2 trials
3 sub-types
- Granulomatous hypophysitis 0 trials
- Immunotherapy induced hypophysitis 0 trials
- Primary hypophysitis 0 trials Sub-types →
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Necrosis of pituitary 0 trials · 1 incl. sub-types
1 sub-type
- Pituitary gland infarction 0 trials · 1 incl. sub-types Sub-types →
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Empty sella syndrome 0 trials
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Pituitary hypoplasia 0 trials
Most studied deeper sub-types
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New drug combo aims to tame acromegaly hormone levels
Disease control Stopped earlyThis phase 2 trial tests whether adding ALXN2420 (a growth hormone blocker) to standard acromegaly treatment can lower IGF-1 levels more than placebo. About 60 adults with acromegaly who are already on a stable dose of somatostatin analogs will receive either ALXN2420 or placebo …
Phase 2 • Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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New pill shows promise for controlling acromegaly Long-Term
Disease control Stopped earlyThis study looks at the long-term safety and effectiveness of an oral medication called paltusotine for people with acromegaly, a condition where the body makes too much growth hormone. About 43 adults who finished a previous related study will take the drug and be monitored for …
Phase 2 • Sponsor: Crinetics Pharmaceuticals Inc. • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Could a pill replace needles for acromegaly?
Disease control Stopped earlyThis study tests an oral drug called paltusotine for people with acromegaly, a condition where the body makes too much growth hormone. Participants had their disease under control with standard injections and were randomly assigned to receive either paltusotine or a placebo. The …
Phase 3 • Sponsor: Crinetics Pharmaceuticals Inc. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New pill could tame rare growth disorder without surgery
Disease control Stopped earlyThis study tests an oral drug called paltusotine in 111 adults with acromegaly, a condition causing abnormal growth due to high hormone levels. Participants are not currently on other treatments. The main goal is to see if the drug safely lowers insulin-like growth factor-1 (IGF-…
Phase 3 • Sponsor: Crinetics Pharmaceuticals Inc. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Can a daily injection reshape bodies of HIV patients?
Disease control Stopped earlyThis study looked at whether tesamorelin (Egrifta), a daily injection that boosts growth hormone, can improve body composition in people with HIV who have excess belly fat (lipodystrophy). Six participants received the drug for up to 12 months, with researchers measuring liver fa…
Phase 4 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New 12-Week hormone therapy studied for rare tumors
Disease control Stopped earlyThis early-phase study tested a new formulation of octreotide (Debio 4126) that lasts 12 weeks, aiming to control hormone levels in people with acromegaly or certain neuroendocrine tumors. Only 19 participants were enrolled before the trial was terminated. The main goal was to me…
Phase 1 • Sponsor: Debiopharm International SA • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New oral test could replace painful insulin injections for hormone diagnosis
Diagnosis Stopped earlyThis study tested a new oral drink (GS3-007a) to diagnose adult growth hormone deficiency (AGHD). It compared the drink to the standard insulin tolerance test in 120 adults suspected of having AGHD and healthy volunteers. The goal was to see if the oral test works as well as the …
Phase 2 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Diagnosis
Last updated Jun 27, 2026 12:37 UTC
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New survey aims to better measure life quality in pituitary tumor patients
Knowledge-focused Stopped earlyThis study tested a new questionnaire called Prolac-10 to see if it can accurately measure quality of life in people with prolactinoma (a type of pituitary tumor) who are starting medical treatment. Only 8 people took part before the study was stopped early. The goal was to check…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC